Avram Herško

Avram Herško
Avram Herško
Ime po rođenju	Avram Hershko
Datum rođenja	(1937-12-31)31. decembar 1937.
Mesto rođenja	Karcag  Mađarska
Državljanstvo	Izrael, Švajcarska
Zanimanje	Hemičar

Avram Hershko (hebr. אברהם הרשקו; rođen 31. decembra 1937) izraelski je biohemičar mađarskog porekla. On je nagrađen Nobelovom nagradom za hemiju 2004. godine.^[1][2]

Publikacije

• Hershko, A., Ciechanover, A., Heller, H., Haas, A.L., and Rose I.A. (1980) "Proposed role of ATP in protein breakdown: Conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis". Proc. Natl. Acad. Sci. USA 77, 1783–1786.
• Hershko, A., Heller, H., Elias, S. and Ciechanover, A. (1983) Components of ubiquitin-protein ligase system: resolution, affinity purification and role in protein breakdown. J. Biol. Chem. 258, 8206–8214.
• Hershko, A., Leshinsky, E., Ganoth, D. and Heller, H. (1984) ATP-dependent degradation of ubiquitin-protein conjugates. Proc. Natl. Acad. Sci. USA 81, 1619–1623.
• Hershko, A., Heller, H., Eytan, E. and Reiss, Y. (1986) The protein substrate binding site of the ubiquitin-protein ligase system. J. Biol. Chem. 261, 11992-11999.
• Ganoth, D., Leshinsky, E., Eytan, E., and Hershko, A. (1988) A multicomponent system that degrades proteins conjugated to ubiquitin. Resolution of components and evidence for ATP-dependent complex formation. J. Biol. Chem. 263, 12412-1241.
• Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F.C., Ruderman, J.V. and Hershko, A. (1995). The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6, 185–198.

Reference

1. Nobel citation
2. Avram Hershko & Aaron Ciechanover, 2004 Nobel in Chemistry Архивирано децембар 19, 2005 на сајту Wayback Machine – A web article

Spoljašnje veze

• Nobel Prize lecture
• Website at the Technion
• Avram Hershko's Short Talk: "Lessons from My Life in Science"
• "Hungarian" Nobel Prize winners Crooked Timber
• Avram Hershko Jewish Virtual Library
• Ubiquitin-Mediated Protein Degradation: From the lab to the bedside Dan Hersko
• The Official Site of Louisa Gross Horwitz Prize