Analogni pirimidini

Analogni pirimidini su antimetaboliti, koji imitiraju strukturu metaboličkih pirimidina.

Primeri

• 5-flourouracil^[1] (5FU) koji inhibira timidilat sintazu.^[2]
• Floksuridin (FUDR)
• Citozin arabinozid (Citarabin)

• 
  Pirimidin
• 
  Fluorouracil
• 
  Floksuridin
• 
  Gemcitabin

Reference

1. Huhtala A, Rönkkö S, Teräsvirta M, et al. (May 2009). „The effects of 5-fluorouracil on ocular tissues in vitro and in vivo after controlled release from a multifunctional implant”. Invest. Ophthalmol. Vis. Sci. 50 (5): 2216–23. DOI:10.1167/iovs.08-3016. PMID 19136700. 
2. Xi Y, Formentini A, Nakajima G, Kornmann M, Ju J (January 2008). „Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer”. Oncol. Rep. 19 (1): 257–62. PMID 18097604.