氯喹酮

氯喹酮
臨床資料
懷孕分級
  • ?
给药途径?
ATC碼
  • 未分配
藥物動力學數據
生物利用度?
药物代谢?
生物半衰期?
排泄途徑?
识别信息
  • 3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone
CAS号25509-07-3  checkY
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
ECHA InfoCard100.042.761 編輯維基數據鏈接
化学信息
化学式C16H12Cl2N2O
摩尔质量319.185
3D模型（JSmol（英语：JSmol））
  • Clc3cccc(Cl)c3N/1C(=O)c2c(\N=C\1CC)cccc2
  • InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3 checkY
  • Key:SONHVLIDLXLSOL-UHFFFAOYSA-N checkY

氯喹酮（英语：Cloroqualone）是一种喹唑啉酮类GABA能药物，是80年代开发的甲喹酮的类似物，主要在法国和其他一些欧洲国家销售。由于其对σ1受体和GABAA受体的β亚型的激动剂活性，它具有镇静和镇咳特性，并且作为止咳药单独或与其他成分组合出售。氯喹酮的镇静作用比甲喹酮弱，因其有效的止咳作用而被出售，但由于担心其可能被滥用和服用过量，于1994年从法国市场撤出。[1]

参见

参考资料

  1. ^ Cloroqualone. PubChem. U.S. National Library of Medicine. [2022-07-29]. （原始内容存档于2019-08-25） （英语）. 

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