TAS2R46

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Receptor ukusa tip 2 član 46
Identifikatori
Simboli	TAS2R46; T2R46; T2R54
Vanjski ID	OMIM: 612774 MGI: 2681256 HomoloGene: 131216 IUPHAR: GeneCards: TAS2R46 Gene
Ontologija gena Molekularna funkcija • aktivnost receptora ukusa Celularna komponenta • integralno sa membranom Biološki proces • signalni put G-protein spregnutog receptora
Ortolozi
Vrsta	Čovek	Miš
Entrez	259292	387348
Ensembl	ENSG00000226761	ENSMUSG00000059382
UniProt	P59540	Q7M721
RefSeq (mRNA)	NM_176887.2	NM_207023
RefSeq (protein)	NP_795368.2	NP_996906
Lokacija (UCSC)	Chr 12: 11.21 - 11.21 Mb	Chr 6: 132.62 - 132.62 Mb
PubMed pretraga	[1]	[2]

Receptor ukusa tip 2 član 46 je protein koji je kod ljudi kodiran TAS2R46 genom.^[1][2]

Reference

1. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). „The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides”. Nat Genet 32 (3): 397–401. DOI:10.1038/ng1014. PMID 12379855. 
2. „Entrez Gene: TAS2R46 taste receptor, type 2, member 46”. 

Literatura

• Margolskee RF (2002). „Molecular mechanisms of bitter and sweet taste transduction.”. J. Biol. Chem. 277 (1): 1–4. DOI:10.1074/jbc.R100054200. PMID 11696554. 
• Montmayeur JP, Matsunami H (2002). „Receptors for bitter and sweet taste.”. Curr. Opin. Neurobiol. 12 (4): 366–71. DOI:10.1016/S0959-4388(02)00345-8. PMID 12139982. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Zhang Y, Hoon MA, Chandrashekar J, et al. (2003). „Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.”. Cell 112 (3): 293–301. DOI:10.1016/S0092-8674(03)00071-0. PMID 12581520. 
• Conte C, Ebeling M, Marcuz A, et al. (2003). „Identification and characterization of human taste receptor genes belonging to the TAS2R family.”. Cytogenet. Genome Res. 98 (1): 45–53. DOI:10.1159/000068546. PMID 12584440. 
• Fischer A, Gilad Y, Man O, Pääbo S (2005). „Evolution of bitter taste receptors in humans and apes.”. Mol. Biol. Evol. 22 (3): 432–6. DOI:10.1093/molbev/msi027. PMID 15496549. 
• Go Y, Satta Y, Takenaka O, Takahata N (2006). „Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.”. Genetics 170 (1): 313–26. DOI:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053. 

Povezano

• Receptor ukusa