Nordazepam

Nordazepam
Alerta sobre risco à saúde
Nome IUPAC 7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Identificadores
Número CAS 1088-11-5
PubChem 2997
DrugBank none
ChemSpider 2890
Código ATC N05BA16
SMILES
InChI
1/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
Propriedades
Fórmula química C15H11ClN2O
Massa molar 270.71 g mol-1
Farmacologia
Biodisponibilidade ?
Via(s) de administração Oral
Metabolismo Hepático
Meia-vida biológica 36-200 houras[1]
Excreção Renal
Classificação legal


Schedule IV (US)

Riscos na gravidez
e lactação 		?
Compostos relacionados
Benzodiazepínicos relacionados 5-Fenil-1H-benzo[e][1,4]diazepin-2(3H)ona (sem o cloro na posição 2' )
Diazepam (metil na posição 1)
Oxazepam (hidroxila na posição 3)
Demoxepam (hidroxila na posição 4)
Delorazepam (cloro na posição 2' )
Nortetrazepam (tetraidro em 2',3',4',5' )
Nitrazepam (nitro em vez de cloro na posição 7)
Página de dados suplementares
Estrutura e propriedades n, εr, etc.
Dados termodinâmicos Phase behaviour
Solid, liquid, gas
Dados espectrais UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a
materiais sob condições normais de temperatura e pressão
Referências e avisos gerais sobre esta caixa.
Alerta sobre risco à saúde.

Nordazepam(DCI; ou nordiazepam; nome comercial: Sopax) é uma substância utilizada como medicamento pertencente ao grupo e sub-grupos:

Indicações

  • Perturbações da ansiedade e sintomas ansiosos.
  • Insónia (Só para tratamento de curto prazo).

Reacções adversas

Contraindicações e precauções

Interacções

Deve ser evitado o uso concomitante de álcool e medicamentos depressores do Sistema Nervoso Central..

Farmacocinética

  • Nordazepam atravessa a barreira placentária e aparece em pequenas doses no leite materno.
  • É absorvido no trato gastrointestinal.
  • O nordazepam apresenta uma semi-vida que varia entre dois a cinco dias.

Excreção


Ver também

Referências

  1. ↑ C. Heather Ashton (2007). «Benzodiazepine Equivalence Table». benzo.org.uk. Consultado em 5 de abril de 2009 

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