4-甲基苯胺

4-甲基苯胺
别名	对甲基苯胺
识别
CAS号	106-49-0
PubChem	7813
性质
化学式	C7H9N
摩尔质量	107.15 g·mol−1
密度	1.046 g·cm−3
熔点	44—45 °C（317—318 K）
沸点	200.4 °C（473.5 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

4-甲基苯胺是有机化合物，化学式C₇H₉N，是甲苯胺的同分异构体。

合成

4-甲基苯胺可由氢气^[2]、水合肼^[3]、硼氢化钠^[4]、铝汞齐^[5]等还原剂还原4-硝基甲苯得到。

反应

氨基的反应

4-甲基苯胺可以和酰卤或酸酐反应得到相应酰胺，如和对甲苯磺酰氯反应，得到N-(对甲苯基)对甲苯磺酰胺^[6]；和乙酸酐反应，得到N-对甲基苯基乙酰胺；^[7]和酸或卤代烃反应，得到4-甲基苯铵盐或相应的季铵盐；^[8]和醛反应，生成氮－碳偶联的产物，如：^[9]

苯环的取代反应

和N-溴代丁二酰亚胺反应得到2-溴-4-甲基苯胺；^[10]碘和二甲基亚砜存在時和4-氟苯硫酚在二甲基甲酰胺反应，可得到取代氨基邻位的产物2-(4-氟苯硫基)-4-甲基苯胺；^[11]和甲醛反應生成Tröger氏鹼。

参考文献

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