Arp2/3 complex (Actin Related Protein 2/3 complex) is a seven-subunit protein complex that plays a major role in the regulation of the actin cytoskeleton...

been determined. However, it is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to...

domain near the WASp C-terminus that binds to and activates the Arp2/3 complex. Activated Arp2/3 nucleates new F-actin. WASp is the founding member of a gene...

protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. This gene encodes one of seven subunits of the human Arp2/3 protein...

filament, Arp2/3 requires a "mother" filament, monomeric ATP-actin, and an activating domain from Listeria ActA or the VCA region of N-WASP. The Arp2/3 complex...

nucleator in F-actin formation assays with brain cytosol depleted for the Arp2/3 complex (the only other actin nucleator known at this time) and with beads...

throughout. Arp2/3 complexes are present at microfilament-microfilament junctions in lamellipodia, and help create the actin meshwork. Arp2/3 can only join...

protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene. This gene encodes one of seven subunits of the Arp2/3 protein complex...

protein 2/3 complex subunit 2 is a protein that in humans is encoded by the ARPC2 gene. This gene encodes one of seven subunits of the human Arp2/3 protein...

two free G-actin molecules, then recruit and activate the Arp2/3 complex. The activated Arp2/3 complex attaches to an existing actin filament, and uses...

seven-protein Arp2/3 nucleation complex, which resembles two actin monomers and therefore allows for easier formation of the polymerization nucleus. Arp2/3 is able...

recruitment of Arp2/3 complex. CDC42, protein tyrosine kinase, phosphoinositide 3-kinase, and Src-family kinases then activate Arp2/3. This causes the...

composition, structure and biosynthesis. Bannerstone House: Charles C Thomas. pp. 3–6. ISBN 978-0-398-02283-9. Wang B, Yang W, McKittrick J, Meyers MA (March...

activity with actin The Arp2/3 complex and cofilin work together to reorganize the actin filaments in the cytoskeleton. Arp 2/3, an actin binding proteins...

two-thirds. Inhibiting Arp2/3 directly resulted in different effects depending on cell type. In human eye cells and macrophages, blocking Arp2/3 led to a decrease...

The major tau protein in the human brain is encoded by 11 exons. Exons 2, 3 and 10 are alternatively spliced, which leads to the formation of six tau...

transformations, cytoplasmic streaming, and calcium-mediated reactions. The Arp2/3 complex plays a crucial role in regulating actin polymerization and organization...

membrane-spanning region. In a mammalian cell, the bacterial ActA interacts with the Arp2/3 complex and actin monomers to induce actin polymerization on the bacterial...

periphery. It is present in all cell types. When activated, it will recruit Arp2/3 complex proteins to existing actin microfilaments, facilitating and stabilizing...

Anatomy & Physiology. Houston: OpenStax CNX. 3.2 The cytoplasm and cellular organelles. ISBN 978-1-947172-04-3. Hardin J, Bertoni G, Kleinsmith LJ (2015)...

protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene. This gene encodes one of seven subunits of the human Arp2/3 protein...

13A – KIF13A, 13B – KIF13B = kinesin-3 14 – KIF14 = kinesin-3 15 – KIF15 = kinesin-12 16B – KIF16B = kinesin-3 17 – KIF17 = kinesin-2 18A – KIF18A, 18B...

in the formation of the actin cytoskeleton through interaction with the Arp2/3 complex. The holocomplex comprises WAVE1 (also known as WASF1), CYFIP1,...

formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the...

of the turn. There are other alternative architectures, such as 11-3, 12-3, 14-3, 15-4, or 16-4, that have been detected at a much lower occurrence....

000 amino acid residues in length. The exception is the small cardiac novex-3 isoform, which is only 5,604 amino acid residues in length. The following...

sides of F-actin. The cell employs Arp2/3 complex to temporarily bind to existing polymers at a 70° angle. The Arp2/3 complex then elongates into a filamentous...

Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II cytokeratin. It is specifically found...

the Arp2/3 complex and WASP family proteins in the control of actin filament assembly, and to show through in vitro biochemistry that the Arp2/3 complex...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

functions to regulate actin filament assembly, possibly by competing with Arp2/3 protein. However, a protein complex including a cadherin, actin, β-catenin...

Tubulin beta-3 chain, Class III β-tubulin, βIII-tubulin (β3-tubulin) or β-tubulin III, is a microtubule element of the tubulin family found almost exclusively...

protein 2/3 complex subunit 5 is a protein that in humans is encoded by the ARPC5 gene. This gene encodes one of seven subunits of the human Arp2/3 protein...

Based on in silico Modeling and Cell Culture". Molecular Informatics. 39 (3) minf.201900035. doi:10.1002/minf.201900035. PMID 31347789. S2CID 198911009...

(chromosome 2q24.11); expressed in striated muscle MYL3 (chromosome 3p21.3); expressed in striated muscle MYL4 (chromosome 17q21.32); expressed in striated...

with cardiac muscle injury. Both markers can be detected in patient's blood 3–6 hours after onset of the chest pain, reaching peak level within 16–30 hours...

structure‑function analyses of actin and critical regulators such as profilin, Arp2/3 complex components, and novel actin nucleation factors. Drubin's group also...

microtubules by binding to the outer surface of the microtubule protofilaments.[3] A single study has suggested that MAP2 and tau bind on the inner microtubule...

stabilize Wiskott–Aldrich syndrome protein (WASp). WASp can then bind the Arp2/3 complex and serve as an actin nucleation point. Subsequent actin polymerization...

Calmodulin-regulated spectrin-associated protein family member 3 (CAMSAP3) is a human protein encoded by the gene CAMSAP3. The protein is commonly referred...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes". J. Biol. Chem. 279 (3): 1607–14. doi:10...

however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to...

Jacobs-Wagner C (August 2005). "Bacterial cell shape". Nature Reviews. Microbiology. 3 (8): 601–610. doi:10.1038/nrmicro1205. PMID 16012516. Iwai N, Nagai K, Wachi...

an inhibitory effect on cellular steady-state F-actin formation via an Arp2/3-dependent mechanism. Whereas coronin 1 was required for chemokine-mediated...

direct target gene in trichocytes". The Journal of Investigative Dermatology. 122 (3): 555–64. doi:10.1111/j.0022-202X.2004.22336.x. PMID 15086535. v t e...

Annexins Aplyronine Archvillin (isoform of Supervillin) Arginine kinase Arp2/3 complex Band 4.1 Band 4.9 (Dematin) b-actinin b-Cap73 Bifocal Bistramide...

populations". Cell Motil Cytoskeleton. 47 (3): 189–208. doi:10.1002/1097-0169(200011)47:3<189::aid-cm3>3.0.co;2-c. PMID 11056521. Lin, JJ; Hegmann, TE;...

human endothelial cells". The Journal of Cell Biology. 81 (3): 570–80. doi:10.1083/jcb.81.3.570. PMC 2110384. PMID 379021. Schweizer J, Bowden PE, Coulombe...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

oxidative muscle fibers. Some of ACTN2 is seen in the brain. Alpha-actinin 3 (ACTN3) is typically found in type II muscle fibers, commonly known as fast...

"Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions". Journal of Molecular Biology. 163 (4): 673–678. doi:10...

"Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo". The Journal of Biological Chemistry. 275...

1999). "The Arp2/3 complex: a multifunctional actin organizer". Current Opinion in Cell Biology. 11 (1): 117–21. doi:10.1016/S0955-0674(99)80014-3. PMID 10047519...

human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. v t e...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the...

Arp2/3 complex, which generates branched actin filaments. Several proteins can serve as NPFs, and it has been observed that in WAS platelets the Arp2/3...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

OMIM accessions: Slow-twitch skeletal muscle isoform troponin I, TNNI1 (1q31.3, 191042) Fast-twitch skeletal muscle isoform troponin I, TNNI2 (11p15.5, 191043)...

properties of Glu-50 protein". Journal of Biochemistry. 93 (3): 825–831. doi:10.1093/jb/93.3.825. PMID 6135695. Maruyama K, Sugano S (January 1994). "Oligo-capping:...

regulation and dynamics, including formins, with roles in actin polymerization, Arp2/3 complexes that give rise to actin branching and capping proteins. Due to...

639-3 code: arp), a Native American language AARP, formerly the American Association of Retired Persons Actin-related protein, for example Arp10) Arp2/3 complex...

isoform expressed in cardiac muscle. The DSP gene is located on chromosome 6p24.3, containing 24 exons and spanning approximately 45 kDa of genomic DNA. Desmoplakin...

filamins". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1538 (2–3): 99–117. doi:10.1016/s0167-4889(01)00072-6. PMID 11336782. Guyon JR, Kudryashova...

"Lamins and Apoptosis". The Journal of Cell Biology. 153 (3): f5–f7. doi:10.1083/jcb.153.3.f5. ISSN 0021-9525. PMC 2190563. PMID 11331313. Gruenbaum,...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

physiological substrate of PKBalpha using KESTREL". The Biochemical Journal. 384 (Pt 3): 489–94. doi:10.1042/BJ20041058. PMC 1134134. PMID 15461588. Alberts, Bruce...

G proteins. Rho GTPases are able to activate WASp which in turn activate Arp2/3 complex which serve as nucleation sites for actin polymerization. The actin...

heterogeneity during epidermal differentiation". Journal of Molecular Biology. 170 (3): 651–673. doi:10.1016/s0022-2836(83)80126-0. PMID 6195345. Jungersted JM...

ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott–Aldrich syndrome...

with protein 4.1 and ankyrin, with the transmembrane ion transporter band 3 Protein 4.2 binds the spectrin tail region to the transmembrane protein glycophorin...

primary structures of FtsZ and tubulin reveal a weak relationship, their 3-dimensional structures are remarkably similar. Furthermore, like tubulin,...

2006). "p120-catenin mediates inflammatory responses in the skin". Cell. 124 (3): 631–44. doi:10.1016/j.cell.2005.11.043. PMC 2443688. PMID 16469707. Brigidi...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

leading to its nucleotide-driven dynamic instability". The EMBO Journal. 27 (3): 570–9. doi:10.1038/sj.emboj.7601978. PMC 2241650. PMID 18188150. Garner...

Katanin, a microtubule severing protein". Cell Biology International. 27 (3): 279. doi:10.1016/s1065-6995(02)00324-4. PMID 12681335. S2CID 36263251. Mellet...

malformation gene-1 (CCM1) encoding KRIT1". Biochimica et Biophysica Acta. 1517 (3): 464–7. doi:10.1016/s0167-4781(00)00303-1. PMID 11342228. "Entrez Gene: KRIT1...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

secretion-system effector) triggers actin reorganization by N-WASP recruitment of Arp2/3 complexes, promoting cell-to-cell spread. The Type III Secretion System...

mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. v t e...

mRNA in trophoblastic cells by cAMP". Mol. Endocrinol. 4 (3): 370–4. doi:10.1210/mend-4-3-370. PMID 1692965. Waseem A, Alexander CM, Steel JB, Lane EB...

"Tails of unconventional myosins". Cellular and Molecular Life Sciences. 56 (3–4): 243–257. doi:10.1007/s000180050426. PMC 11147021. PMID 11212352. S2CID 23407921...

molecular weight protein in non-muscle cells". Journal of Molecular Biology. 115 (3): 465–83. doi:10.1016/0022-2836(77)90166-8. PMID 563468. Rodríguez del Río...

be detrimental to cytoskeleton formation as well as an increase in caspase 3 activity, which would lead to increased apoptosis of cells with these mutations...

analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. Simpson JC, Wellenreuther...

glycine loops". Proc. Natl. Acad. Sci. U.S.A. 89 (3): 910–4. Bibcode:1992PNAS...89..910K. doi:10.1073/pnas.89.3.910. PMC 48354. PMID 1371013. Tkachenko AV,...

protein normally builds a "destruction complex" with glycogen synthase kinase 3-alpha and/or beta (GSK-3α/β) and Axin via interactions with the 20 AA and...

stabilization by polymerization-driven CAMSAP deposition". Developmental Cell. 28 (3): 295–309. doi:10.1016/j.devcel.2014.01.001. PMID 24486153. Tanaka N, Meng...

Science. 99 ( Pt 3) (3): 627–636. doi:10.1242/jcs.99.3.627. PMID 1939373. Ueyama H, Ohsugi R (March 1990). "TaqI polymorphism in the 3' flanking region...

cytokeratins 10, 13, 14 and 19 in oral lichen planus" (PDF). J Oral Sci. 51 (3): 355–65. doi:10.2334/josnusd.51.355. PMID 19776502. Sheng S, Barnett DH,...

CACO-2 epithelial cells". The Journal of Cell Biology. 146 (3): 645–58. doi:10.1083/jcb.146.3.645. PMC 2150552. PMID 10444072. Whittock NV, Eady RA, McGrath...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

a protein domain repeat perspective". Journal of Structural Biology. 179 (3): 289–298. doi:10.1016/j.jsb.2012.02.010. PMC 3728663. PMID 22414427. Stossel...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

"Microtubule dynamics". Journal of Cell Science. 115 (Pt 1): 3–4. doi:10.1242/jcs.115.1.3. PMID 11801717. Howard J, Hyman AA (April 2003). "Dynamics and...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

for Flagellar Assembly". The Journal of Cell Biology. 144 (3): 473–481. doi:10.1083/jcb.144.3.473. ISSN 0021-9525. PMC 2132917. Porter, Mary E.; Bower,...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

1997). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. "Entrez Gene: MYO1F myosin...

human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. Raica M, Zylis...

of the integumental scale armour". European Journal of Histochemistry. 57 (3): e27. doi:10.4081/ejh.2013.e27. PMC 3794358. PMID 24085276. Calvaresi M,...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

binding to myosin heavy chain". Am. J. Physiol. 275 (3 Pt 1): C870–81. doi:10.1152/ajpcell.1998.275.3.C870. PMID 9730972. Weiss A, McDonough D, Wertman B...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

(2011 ed.). Springer, Berlin, Heidelberg. p. 252. doi:10.1007/978-3-642-16483-5. ISBN 978-3-642-16483-5. S2CID 27502611. Miller RK, Hong JY, Muñoz WA, McCrea...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

ring and constriction occurs in the last part of the cell cycle. In 1992-3 three labs independently discovered that FtsZ was related to eukaryotic tubulin...

co-express (along with vinculin) a splice variant carrying an extra exon in the 3' coding region, thus encoding a longer isoform meta-vinculin (meta VCL) of...

right ventricular cardiomyopathy". The American Journal of Cardiology. 111 (3): 400–405. doi:10.1016/j.amjcard.2012.10.017. PMC 3554957. PMID 23168288....

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

is subsequently removed". Molecular and Cellular Biology. 3 (5): 787–95. doi:10.1128/mcb.3.5.787. PMC 368601. PMID 6865942. "Entrez Gene: ACTA1 actin...

keratins K6a, K16 and K17 causing pachyonychia congenita". J. Dermatol. Sci. 48 (3): 199–205. doi:10.1016/j.jdermsci.2007.07.003. PMID 17719747. Barcelos AC...

2p13.1 and molecular nature of the hindIII polymorphism". Genomics. 25 (3): 720–3. doi:10.1016/0888-7543(95)80016-F. PMID 7759108. Szucsik JC, Lessard JL...

long-established genes on the human lineage". PLOS Comput. Biol. 3 (12): e247. Bibcode:2007PLSCB...3..247Z. doi:10.1371/journal.pcbi.0030247. PMC 2134963. PMID 18085818...

"Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway". Proceedings of the National Academy of Sciences of the...

head domain, and a C-terminal tail domain. The isoform of syncoilin, SYNC 3, has a much different structure than the original protein filament. This isoform...

analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. "Entrez Gene:...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

antiparallel, unstaggered tetramers or antiparallel, staggered tetramers. Step 3: the dimers may also associate longitudinally with a short head-to-tail overlap...

recognition of a wide range of membrane proteins. These 24 repeats contain 3 structurally distinct binding sites ranging from repeat 1-14. These binding...

LMNA, LMNB1, and LBR by fluorescence in situ hybridization". Genomics. 32 (3): 474–478. doi:10.1006/geno.1996.0146. PMID 8838815. Buxboim A, Swift J, Irianto...

molecules (integrins/cadherins) in prostate cancer". Int Braz J Urol. 37 (3): 302–6. doi:10.1590/S1677-55382011000300002. PMID 21756376. Zhang F, Meng...

(15): 1326–1330. Bibcode:2002CBio...12.1326P. doi:10.1016/s0960-9822(02)01033-3. PMID 12176362. Bechstedt S, Brouhard GJ (July 2012). "Doublecortin recognizes...

PMID 19262145. Pollard TD (June 2007). "Regulation of actin filament assembly by Arp2/3 complex and formins". Annual Review of Biophysics and Biomolecular Structure...

interspecies conservation of 3' untranslated regions". Molecular and Cellular Biology. 3 (10): 1738–1745. doi:10.1128/mcb.3.10.1738. PMC 370035. PMID 6646120...

dimers and trimers are energetically unfavorable. Actin nucleators like the Arp2/3 complex of proteins from the formin family are most frequently involved...

Tropomodulin-3 is a protein that in humans is encoded by the TMOD3 gene. Tropomodulin-3 (Tmod3) is a member of the tropomodulin family of actin-regulatory...

ADF/cofilin family: actin-remodeling proteins". Genome Biol. 3 (5) reviews3007. doi:10.1186/gb-2002-3-5-reviews3007. PMC 139363. PMID 12049672. Samstag Y, Nebl...

Intermediate Filaments: A Review, Springer Berlin Heidelberg, p. 33, ISBN 978-3-642-70230-3 Karabinos A, Riemer D, Erber A, Weber K (October 1998). "Homologues...

required for Wnt signaling: possibly to recruit various coactivators, such as 14-3-3zeta. Yet its exact partners among the general transcription complexes are...

1002/humu.10302. PMID 14695531. S2CID 20671312. "Entrez Gene: C3orf10 chromosome 3 open reading frame 10". Cascón A, Escobar B, Montero-Conde C, Rodríguez-Antona...

Excretion of Uromodulin". Journal of the American Society of Nephrology. 33 (3): 511–529. doi:10.1681/ASN.2021040491. PMC 8975067. PMID 35228297. v t e...

phosphotyrosine-containing proteins in T lymphocytes". Biochem. Biophys. Res. Commun. 224 (3): 666–74. doi:10.1006/bbrc.1996.1082. PMID 8713105. Mukai H, Toshimori M,...

escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation". PLOS Pathogens. 6 (8) e1001041....

human beta-tubulin isotypes". Molecular and Cellular Biology. 3 (5): 854–62. doi:10.1128/mcb.3.5.854. PMC 368608. PMID 6865944. Andersson B, Wentland MA,...

significantly elevates the cardiac troponin T levels in the blood stream. 3% of the study subjects have shown elevated amounts of the protein after their...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms". Translational Psychiatry. 11 (1):...

metastasis and the energetics of cell biology. She discovered the 7-subunit Arp2/3 complex and showed that this was a major regulator of actin dynamics and...

resistance to androgen deprivation". The American Journal of Pathology. 181 (3): 1007–16. doi:10.1016/j.ajpath.2012.06.008. PMC 3432435. PMID 22819534. Davani...

for metastatic phenotypes of lung cancer cells". Clin. Exp. Metastasis. 20 (3): 189–93. doi:10.1023/A:1022978932215. PMID 12741677. S2CID 22741542. Dunham...

16 and keratin 17 mutations cause pachyonychia congenita". Nat. Genet. 9 (3): 273–8. doi:10.1038/ng0395-273. PMID 7539673. S2CID 1873772. Bowden PE, Haley...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

"[Pulmonary edema in hangings]". De l'Anesthésiologie Française. 16. 16 Spec No 2-3: 57–65. PMID 9873. Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura...

Tropomyosin alpha-3 chain is a protein that in humans is encoded by the TPM3 gene. This gene encodes a member of the tropomyosin family of actin-binding...

protein associated with desmin and vimentin filaments in muscle". Cell. 22 (3): 727–738. doi:10.1016/0092-8674(80)90549-8. PMID 7006832. S2CID 24349058...

result of hyperactivity and impaired learning and memory. TMOD3 Tropomodulin 3 (TMOD3) is found to be essential in membranous skeleton and embryonic development...

GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, HER2/neu, Metabotropic glutamate receptor 3, and Metabotropic glutamate receptor 7. GRCh38: Ensembl release 89: ENSG00000100151...

transitional cell carcinoma of the urinary bladder". Int. J. Cancer. 110 (3): 368–73. doi:10.1002/ijc.20151. PMID 15095301. S2CID 875146. Kimura K, Wakamatsu...

1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. Weil D, Blanchard S, Kaplan...

protein 2/3 complex subunit 4 is a protein that in humans is encoded by the ARPC4 gene. This gene encodes one of seven subunits of the human Arp2/3 protein...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–439. doi:10.1006/geno.1996.0488. PMID 8884266. "Entrez Gene: MYO1E myosin...

actin cytoskeleton through the Arp2/3 complex". Current Biology. 8 (25): 1347–1356. doi:10.1016/s0960-9822(98)00015-3. ISSN 0960-9822. PMID 9889097. S2CID 16661755...

spliced exon of dystrophin". The Journal of Cell Biology. 128 (3): 363–71. doi:10.1083/jcb.128.3.363. PMC 2120343. PMID 7844150. Khan R (January 25, 2011)...

induced by phorbol ester in HT 1080 fibrosarcoma cells". FEBS Lett. 537 (1–3): 91–5. doi:10.1016/S0014-5793(03)00098-X. PMID 12606037. S2CID 44551128....

implications for isoform evolution and function". Mol Cell Biol. 10 (3): 1095–104. doi:10.1128/mcb.10.3.1095. PMC 360973. PMID 2304459. Lenz S, Lohse P, Seidel U...

homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. 260 (1): 296–302. doi:10.1006/bbrc...

Bagheri-Yarmand R, Kumar R (February 2004). "p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate". EMBO Reports...

epidermolysis bullosa simplex". Human Molecular Genetics. 3 (7): 1171–2. doi:10.1093/hmg/3.7.1171. PMID 7526926. Hovnanian A, Pollack E, Hilal L, Rochat...

N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility". The Journal of Cell Biology...

(2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization"...

neural differentiation using quantitative proteomics". J. Proteome Res. 8 (3): 1315–26. doi:10.1021/pr8006667. PMC 2693473. PMID 19173612. Odell AF, Van...

with keratin 18". J. Cell. Biochem. 72 (3): 356–67. doi:10.1002/(SICI)1097-4644(19990301)72:3<356::AID-JCB5>3.0.CO;2-M. ISSN 0730-2312. PMID 10022517...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151. Horisberger MA...

biology of the cell (4th ed.). Garland Science. 2002. ISBN 978-0-8153-3218-3. Eyer J, Leterrier JF (June 1988). "Influence of the phosphorylation state...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

effector cell". The Journal of Experimental Medicine. 163 (3): 489–98. doi:10.1084/jem.163.3.489. PMC 2188060. PMID 3081676. Burn P, Kupfer A, Singer SJ...

molecular weight of roughly 66 kDa and an isoelectric point of roughly 8.3, further confirming that the protein is basic. Keratin 1 often dimerizes with...

isolation and its interaction with Munc13". Biochem. Biophys. Res. Commun. 248 (3): 846–51. doi:10.1006/bbrc.1998.9067. PMID 9704016. De Matteis MA, Morrow...

plectin knockout mouse have shed light on the functions of plectin. Pups died 2–3 days after birth, and these mice exhibited marked skin abnormalities, including...

GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of...

distinct isotype". J Mol Biol. 182 (1): 11–20. doi:10.1016/0022-2836(85)90023-3. PMID 3999141. "Entrez Gene: TUBB2C tubulin, beta 2C". Kulkarni, Sumeet (2024-04-02)...

subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome". American Journal of Human Genetics. 46 (3): 559–567. PMC 1683621...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

distribution of plakoglobin due to mutations in genes encoding for Desmoglein 1 and 3 have also been implicated in Pemphigus vulgaris. Plakoglobin has been shown...

protein". Cell Motility and the Cytoskeleton. 35 (3): 175–87. doi:10.1002/(SICI)1097-0169(1996)35:3<175::AID-CM1>3.0.CO;2-8. PMID 8913639. Mass spectrometry characterization...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

regulating ATP enzyme activity located in the motor head domain. There are 3 amino acid binding sites essential for myosin-VI's interactions, Arg-Arg-Leu...

Aplysia required for neurotransmitter release". Science. 269 (5230): 1580–3. Bibcode:1995Sci...269.1580S. doi:10.1126/science.7667638. PMID 7667638....

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

of branched actin filaments. Therefore, proteins that interact with the arp2/3 complex as well as F-actin are under investigation for involvement in this...

interacts with myosin-1 and enhances myosin-1 mediated activation of the Arp2/3 complex. In addition to a role in endocytosis, Saccharomyces cerevisiae...

the microfibrils are composed of end-to-end polymers of fibrillin. To date, 3 forms of fibrillin have been described. The fibrillin-1 protein was isolated...

Ankyrin-3 (ANK-3), also known as ankyrin-G, is a protein from ankyrin family that in humans is encoded by the ANK3 gene. The protein encoded by this gene...

Cancer. 30 (2): 123–35. doi:10.1002/1098-2264(2000)9999:9999<::AID-GCC1070>3.0.CO;2-W. PMID 11135429. S2CID 40237049. Schweizer J, Bowden PE, Coulombe...

human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. Olsen JV, Blagoev...

regulation of the mitotic spindle". FEBS Lett. 514 (2–3): 193–8. doi:10.1016/S0014-5793(02)02363-3. PMID 11943150. S2CID 2579290. Tirnauer JS, Bierer BE...

of a human perinatal myosin heavy-chain transcript". Eur. J. Biochem. 230 (3): 1001–6. doi:10.1111/j.1432-1033.1995.tb20648.x. PMID 7601129. Soussi-Yanicostas...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

plasticity in actin and tubulin polymer dynamics". Science. 325 (5943): 960–3. Bibcode:2009Sci...325..960K. doi:10.1126/science.1168823. PMC 2864651. PMID 19696342...

reveals constant and variable structural domains among keratins". Cell. 33 (3): 915–924. doi:10.1016/0092-8674(83)90034-X. PMID 6191871. S2CID 21490380...

human and mouse". Biochemical and Biophysical Research Communications. 270 (3): 1111–1118. Bibcode:2000BBRC..270.1111S. doi:10.1006/bbrc.2000.2571. PMID 10772959...

cornea-specific keratin 12 gene in Meesmann corneal dystrophy". Jpn. J. Ophthalmol. 52 (3): 224–6. doi:10.1007/s10384-007-0518-2. PMID 18661274. S2CID 189791983. Corden...

proteins and performance in human heart failure". Heart Failure Reviews. 10 (3): 187–197. doi:10.1007/s10741-005-5249-1. PMID 16416042. S2CID 20691228. Harris...

genes (KRT4 and KRT15) by in situ hybridization". Cytogenet. Cell Genet. 54 (3–4): 148–50. doi:10.1159/000132979. PMID 1702379. Schweizer J, Bowden PE, Coulombe...

4.2 is an ATP-binding protein which may regulate the association of band 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property...

Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–320. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151. Maruyama K, Sugano...

dynamin mutant defines a superconstricted prefission state". Cell Reports. 8 (3): 734–742. doi:10.1016/j.celrep.2014.06.054. PMC 4142656. PMID 25088425. Kong...

encoded by the KIF1A gene. KIF1A is a neuron-specific member of the kinesin-3 family and is a microtubule plus end-directed motor protein involved in the...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

colon carcinoma patients]". Zhonghua Zhong Liu Za Zhi (in Chinese). 24 (3): 261–3. PMID 12515621. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane...

genes responsible for hereditary deafness DFNB3 and shaker 2". Genomics. 61 (3): 243–258. doi:10.1006/geno.1999.5976. PMID 10552926. Friedman TB, Liang Y...

Failing Human Heart. Vol. 87. pp. 129–41. doi:10.1007/978-3-642-72474-9_11. ISBN 978-3-642-72476-3. PMID 1386730. {{cite book}}: |journal= ignored (help)...

the DYNC2H1 gene. It is associated with short rib–polydactyly syndrome type 3. It is also associated with asphyxiating thoracic dysplasia. dynein GRCh38:...

investigation of candidate genes". The Journal of Investigative Dermatology. 119 (3): 692–698. doi:10.1046/j.1523-1747.2002.01855.x. PMID 12230514. v t e...

type-II hair keratins". Differentiation; Research in Biological Diversity. 61 (3): 187–194. doi:10.1046/j.1432-0436.1997.6130187.x. PMID 9084137. Schweizer...

regenerative medicine". Expert Opinion on Biological Therapy. 7 (3): 289–91. doi:10.1517/14712598.7.3.289. PMID 17309321. S2CID 1039201. Teranishi N, Naito Z,...

pancreas". The Journal of Pathology. 184 (3): 234–9. doi:10.1002/(SICI)1096-9896(199803)184:3<234::AID-PATH28>3.0.CO;2-D. PMID 9614373. S2CID 19443756....

cytoskeleton through the Arp2/3 complex". Curr. Biol. 8 (25): 1347–56. Bibcode:1998CBio....8.1347M. doi:10.1016/S0960-9822(98)00015-3. PMID 9889097. S2CID 16661755...

and severin. Six large repeating segments occur in gelsolin and villin, and 3 similar segments in severin and fragmin. The multiple repeats are related...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

ATP, and produce force. The neck or light chain binding domain consists of 3 IQ motifs, with each IQ motif providing a binding site for one molecule of...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

identified as conferring a lifetime risk of 50% for carriers. An in-frame 3-bp deletion mutation in MYH6, in which one residue in MHC-α is removed, enhances...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

16 and keratin 17 mutations cause pachyonychia congenita". Nat Genet. 9 (3): 273–8. doi:10.1038/ng0395-273. PMID 7539673. S2CID 1873772. Troyanovsky...

Journal of Cellular Biochemistry. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950. S2CID 46076387....

investigations". The Anatomical Record. 245 (3): 481–7. doi:10.1002/(SICI)1097-0185(199607)245:3<481::AID-AR4>3.0.CO;2-V. PMID 8800406. Wu JC, Sung HC, Chung...

keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep. 20 (3): 155–61. doi:10.1007/BF00990548. PMID 7565656. S2CID 24487602. Schweizer...

brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851. Hazan J, Davoine CS, Mavel D, et al....

other proteins involved in the Notch pathway, including the roles of Wasp/Arp2/3, Sec15, Tempura, and EHBP-1 in Delta processing and signaling. 1983 - Fulbright...

human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. Adkins JN, Varnum...

syndrome protein) are used as markers alongside actin, cortactin and the Arp2/3 complex to localize and isolate these protrusions because Tks5 and WASP...

skin is sufficient to activate keratinocytes". J. Invest. Dermatol. 124 (3): 602–14. doi:10.1111/j.0022-202X.2005.23620.x. PMID 15737202. Takizawa Y...

Human Genetics. 81 (3): 278–82. doi:10.1007/bf00279004. PMID 2784124. S2CID 6703175. "Entrez Gene: MYL3 myosin, light chain 3, alkali; ventricular,...

regions of the fsTnT protein are generated by alternative splicing (Fig. 3). In the N-terminal region of fsTnT, exons 4, 5, 6, 7 and 8 are alternatively...

site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573. Stedman...

1997). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. Donaudy F, Ferrara A, Esposito...

and KRT15) by in situ hybridization". Cytogenetics and Cell Genetics. 54 (3–4): 148–150. doi:10.1159/000132979. PMID 1702379. Schweizer J, Bowden PE,...

DL. 2015 The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit. J Cell Biol. 208:161-170. (Highlighted commentary...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

family-based methods". Neurogenetics. 10 (1): 19–25. doi:10.1007/s10048-008-0151-3. PMC 2841132. PMID 18830724. Shoeman RL, Sachse C, Höner B, et al. (1993)...

therapeutic approach for treating neuromuscular diseases". Nature Medicine. 18 (3): 452–455. doi:10.1038/nm.2618. PMC 3296825. PMID 22344294. Shefner JM, Wolff...

reticulum transport". Molecular and Cellular Biology. 22 (3): 866–873. doi:10.1128/MCB.22.3.866-873.2002. PMC 133549. PMID 11784862. Caballero Oteyza...

hyperplastic human prostate tissue". Prostate. 44 (3): 193–203. doi:10.1002/1097-0045(20000801)44:3<193::AID-PROS3>3.0.CO;2-A. PMID 10906735. S2CID 10058067. Meloni...

of sorting nexin 9 as an accessory protein to AP-2". Biochem. J. 362 (Pt 3): 597–607. doi:10.1042/0264-6021:3620597. PMC 1222423. PMID 11879186. Strausberg...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

They include TEKT1, TEKT2, TEKT3, TEKT4, TEKT5. Tektin filaments are 2 to 3 nm diameter with two alpha helical segments. They have the consensus amino...

found. Two molecules that directly stimulate actin polymerization are the Arp2/3 proteins and the Diaphanous-related formins. Rho/Rac proteins are involved...

MacQuarrie, Cameron Dale (2022-12-04). "Chlorarachniophytes form light- and Arp2/3 complex-dependent extensions that are involved in motility and predation"...

human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. Overview of all...

GTPase-activating protein domain in its tail". J. Cell Sci. 109 (3): 653–61. doi:10.1242/jcs.109.3.653. PMID 8907710. Post PL, Bokoch GM, Mooseker MS (1998)...

BioEssays. 20 (7): 523–7. doi:10.1002/(SICI)1521-1878(199807)20:7<523::AID-BIES1>3.0.CO;2-L. PMID 9722999. Oakley BR (Dec 2000). "An abundance of tubulins"....

essential in normal function of erythrocytes; however, ankyrin-B and ankyrin-3 play essential roles in the localization and membrane stabilization of ion...

HAX-1 is an interleukin-1 alpha N-terminal binding protein". Cytokine. 15 (3): 122–37. doi:10.1006/cyto.2001.0891. PMID 11554782. Wennerberg K, Ellerbroek...

Dystonin (DST), also known as bullous pemphigoid antigen 1 (BPAG1), isoforms 1/2/3/4/5/8, is a protein that in humans is encoded by the DST gene. This gene encodes...

WAVE1-induced actin nucleation by Rac1 and Nck". Nature. 418 (6899): 790–3. Bibcode:2002Natur.418..790E. doi:10.1038/nature00859. PMID 12181570. S2CID 4350733...

remodels Arp2/3-containing actin branches in lamellipodia. F-actin binding is essential for coronin 1B function in vivo. Coronin 1B coordinates Arp2/3 complex...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

Wiskott-Aldrich syndrome protein (N-Wasp) to invadopodia, which requires Arp2/3, to activate actin polymerization and thus invadopodia elongation. A key...

binding sites for TnI and troponin C (TnC) in the C-terminal region (Fig. 3). Consistent with the recessive phenotype, the truncated ssTnT is incapable...

(SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton"...

myoxin (MYH12), the human homologue to the mouse dilute gene". Genomics. 19 (3): 407–416. doi:10.1006/geno.1994.1088. PMID 8188282. Bement WM, Hasson T,...

nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the...

protein, WISH, induces Arp2/3 complex activation independent of Cdc42". The Journal of Cell Biology. 152 (3): 471–82. doi:10.1083/jcb.152.3.471. PMC 2196001...

WAVE (Scar), HSP300, ABL2, SRA1, and NAP1 and others) to associate with Arp2/3, which directly promotes actin polymerization. As actin is accumulated and...

genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. Mayer BJ, Ren R, Clark KL, Baltimore D...

podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex". Nature Communications. 6 (1): 7254. Bibcode:2015NatCo...6.7254P...

hybridization. [email protected]". Cytogenetics and Cell Genetics. 82 (3–4): 267–8. doi:10.1159/000015115. PMID 9858832. S2CID 84466204. Reid E, Dearlove...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

(SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton"...

light chain in skeletal muscle cells". Journal of Molecular Biology. 211 (3): 505–13. doi:10.1016/0022-2836(90)90261-J. PMID 2308163. Timson DJ, Trayer...

and chromosomal localization of a human class III myosin". Genomics. 67 (3): 333–42. doi:10.1006/geno.2000.6256. PMID 10936054. "Entrez Gene: MYO3A myosin...

erythroid alpha spectrin (SPTA1) locus". Hum. Mol. Genet. 1 (3): 218. doi:10.1093/hmg/1.3.218-a. PMID 1339473. Kanzaki A, Rabodonirina M, Yawata Y, et al...

containing the type II hair keratin gene domain". J. Invest. Dermatol. 114 (3): 464–72. doi:10.1046/j.1523-1747.2000.00910.x. PMID 10692104. Hesse M, Magin...

novel cofactor for p300 that regulates the p53 response". Molecular Cell. 4 (3): 365–76. doi:10.1016/S1097-2765(00)80338-X. PMID 10518217. Zuchero JB, Coutts...

genes map to human chromosomes 1q and 17, respectively". Hum Genet. 100 (3–4): 486–8. doi:10.1007/s004390050539. PMID 9272178. S2CID 12384017. "Entrez...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

microtubule-based motor proteins such as dynein and dynactin. In fungal cells lacking Arp2/3, clathin-independent endocytosis seems to be the dominant form of endocytosis...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17". Genomics. 28 (3): 367–76. doi:10.1006/geno.1995.1163. PMID 7490069. Bowden...

chromosome band 3p14.3 and identification of YACs containing the complete FLNB transcribed region". Cytogenet. Cell Genet. 85 (3–4): 267–8. doi:10.1159/000015309...

toxin induces transendothelial cell tunnels, which are resealed by MIM via Arp2/3-driven actin polymerization". Cell Host & Microbe. 10 (5): 464–474. doi:10...

expression of three novel human type-II hair keratins". Differentiation. 61 (3): 187–94. doi:10.1046/j.1432-0436.1997.6130187.x. PMID 9084137. Winter H,...

complex". Proc. Natl. Acad. Sci. U.S.A. 87 (3): 1238–42. Bibcode:1990PNAS...87.1238S. doi:10.1073/pnas.87.3.1238. PMC 53446. PMID 2105501. Bobak DA, Nightingale...

DNA-templated positive regulation of actin nucleation rhythmic process Arp2/3 complex-mediated actin nucleation Sources:Amigo / QuickGO Orthologs Databases...

BTB/kelch repeat family, is mutated in giant axonal neuropathy". Nat Genet. 26 (3): 370–4. doi:10.1038/81701. PMID 11062483. S2CID 2917153. "Entrez Gene: GAN...

neural Wiskott–Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex". The Journal of Biological Chemistry. 275 (29): 21946–52. doi:10...

MYLK2 MYLL1 Other Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors...

homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. 260 (1): 296–302. doi:10.1006/bbrc...

GB (November 2002). "Intraflagellar transport". Nat. Rev. Mol. Cell Biol. 3 (11): 813–25. doi:10.1038/nrm952. PMID 12415299. S2CID 12130216. Nonaka S...

keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep. 20 (3): 155–61. doi:10.1007/BF00990548. PMID 7565656. S2CID 24487602. Schweizer...

its cooperative interaction with spectrin and protein 3". Journal of Cellular Biochemistry. 37 (3): 301–315. doi:10.1002/jcb.240370305. PMID 2970468. S2CID 42349239...

protein, WISH, induces Arp2/3 complex activation independent of Cdc42". The Journal of Cell Biology. 152 (3): 471–82. doi:10.1083/jcb.152.3.471. PMC 2196001...

the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194. Strausberg...

Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene. Myosin is a hexameric ATPase cellular motor protein...

(Jul 2002). "Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers". International Journal of Cancer...

human prostate tissue". The Prostate. 44 (3): 193–203. doi:10.1002/1097-0045(20000801)44:3<193::AID-PROS3>3.0.CO;2-A. PMID 10906735. S2CID 10058067. Nguyen...

Yeung, Rae S. M.; Brumell, John H; Muise, Aleixo M (2017). "Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to...

implications for isoform evolution and function". Mol Cell Biol. 10 (3): 1095–104. doi:10.1128/mcb.10.3.1095. PMC 360973. PMID 2304459. "Entrez Gene: MYL6B myosin...

SK, Goode BL (2009). "The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation". Current Biology. 19...

differential splicing and genomic constraints". Journal of Molecular Evolution. 27 (3): 228–235. Bibcode:1988JMolE..27..228C. doi:10.1007/BF02100079. PMID 3138425...

kinase domain of MYLK2 gene in common human cancers". Pathol. Res. Pract. 202 (3): 137–40. doi:10.1016/j.prp.2005.12.003. PMID 16448786. Gallagher PJ, Herring...

the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194. Strausberg...

is regulated by association between merlin domains". Biochem. J. 358 (Pt 3): 727–35. doi:10.1042/0264-6021:3580727. PMC 1222106. PMID 11535133. Hu RJ...

"Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein". Biochemistry. 41 (17): 5566–72. doi:10.1021/bi015946f. PMID 11969417...

domain of FGD1. As cortactin is known to promote actin polymerization by the Arp2/3 complex, this interaction seems to promote actin assembly. FGD1 is also...

PLEKHA7. In the absence of either PLEKHA7 or PDZD11, the amount of nectin-3 and nectin-4 detected at junctions is decreased, as well as total nectin levels...

(2018). "Biallelic loss of human CTNNA2, encoding αN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migration". Nature...

localization and can be targeted by RXR agonists in vitro". PLOS Pathogens. 18 (3) e1009983. doi:10.1371/journal.ppat.1009983. PMC 8970526. PMID 35312737. Sekine...

Myosin-3 is a protein that in humans is encoded by the MYH3 gene. Myosin is a major contractile protein which converts chemical energy into mechanical...

profiling of breast cancer". Annual Review of Pathology. 3: 67–97. doi:10.1146/annurev.pathmechdis.3.121806.151505. PMID 18039137. Chu PG, Weiss LM (Jan 2002)...

is a large gene spanning more than 106 kilo base pairs on chromosome 22q12.3. It is composed of 41 exons with the first ATG of the open reading frame localized...

The WASP protein family control actin polymerization by activating the Arp2/3 complex. WASP is defective in Wiskott–Aldrich syndrome (WAS) whereby in...

cytoskeletal activity. The kinesin KIF13A and actin machinery (AnxA2 and Arp2/3) appear to interact with BLOC-1 to generate recycling endosomes/recycling...

domain protein syndapin I possibly acts through further interactions with Arp2/3 and N-WASP. The GTPase dynamin then pinches off the large membrane-vacuole...

encoding the fast twitch skeletal muscle troponin I (fsTnI). fsTnI is a 21.3 kDa protein consisting of 182 amino acids including the first methionine with...

(2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization"...

structures depend on actin-polymerizing complexes such as SCAR, WASp, and Arp2/3. The surface receptors cluster into a ring-like adhesion structure around...

et al. (1997). "An EST and STS-based YAC contig map of human chromosome 9q22.3". Genomics. 38 (2): 199–205. doi:10.1006/geno.1996.0616. PMID 8954802. Vera...

sequence, expression, and mapping to human chromosome 2 at 2p23". Genomics. 47 (3): 405–8. doi:10.1006/geno.1997.5123. PMID 9480755. "Entrez Gene: KIF3C kinesin...

LMNA, LMNB1, and LBR by fluorescence in situ hybridization". Genomics. 32 (3): 474–8. doi:10.1006/geno.1996.0146. PMID 8838815. "Entrez Gene: LMNB1 lamin...

mRNA expression showed the greatest change, being upregulated 9.4-fold and 7.3-fold in left and right atria, respectively. In a porcine model of left atrial...

localization to human chromosome 6". Biochem. Biophys. Res. Commun. 279 (3): 879–83. doi:10.1006/bbrc.2000.4028. PMID 11162443. Strausberg RL, Feingold...

clones from cell line KG-1 and brain". DNA Research. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502. Chang NS, Mattison J, Cao H, Pratt...

molecule. The high-resolution crystal structure of human alpha-actinin 2 at 3.5 Å was recently resolved. Alpha actinins belong to the spectrin gene superfamily...

neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438. PMID 12486594. Ota T...

conformation of cCTnC and enhancing its affinity for Ca2+ (from Kd = 40 nM to Kd = 3 nM). cTnT235-286 forms a helical coiled coil with cTnI88-135 that binds to...

kinase with the cytoskeletal protein tau". The Journal of Neuroscience. 22 (3): 698–707. doi:10.1523/JNEUROSCI.22-03-00698.2002. PMC 6758498. PMID 11826099...

gene located at 1p36.2 in neuroblastoma". Int. J. Oncol. 23 (3): 737–44. doi:10.3892/ijo.23.3.737. PMID 12888911. Rodriguez M, Yu X, Chen J, Songyang Z (2004)...

form of peripherin (Per61). In human peripherin, the inclusion of introns 3 and 4, regions that are similarly spliced out of the abundant peripherin protein...

Genomics. 72 (3): 223–230. doi:10.1006/geno.2000.6470. PMID 11401437. Robinson RC, Turbedsky K, Kaiser DA, et al. (2001). "Crystal structure of Arp2/3 complex"...

protein kinase A, protein kinase C, protein kinase G, and p21-activated kinase 3. A significant part of cTnI released into the patient's bloodstream is phosphorylated...

regulation during endocytosis. Budding yeast Bbc1 inhibits the activator of the Arp2/3 complex Las17 (WASp homolog). The protein also interacts with the tail of...

integrating cells into tissues". Physiological Reviews. 81 (3): 1353–1392. doi:10.1152/physrev.2001.81.3.1353. PMID 11427698. S2CID 15307181. Bennett V (October...

gene". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1359 (3): 181–186. doi:10.1016/s0167-4889(97)00103-1. PMID 9434124. "Entrez Gene:...

ISSN 1939-8697. PMID 29220227. Li, Zhi; Kim, Eric S.; Bearer, Elaine L. (2002). "Arp2/3 complex is required for actin polymerization during platelet shape change"...

B (Aug 2003). "A novel myosin heavy chain gene in human chromosome 19q13.3". Gene. 312: 165–71. doi:10.1016/S0378-1119(03)00613-9. PMID 12909352. Donaudy...

Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. Strausberg RL...

are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53". J. Neurosci. 23 (4): 1310–9...

expression of three novel human type-II hair keratins". Differentiation. 61 (3): 187–94. doi:10.1046/j.1432-0436.1997.6130187.x. PMID 9084137.{{cite journal}}:...

regulates the aggregation of mutant huntingtin protein". Nature Cell Biology. 4 (3): 240–5. doi:10.1038/ncb761. PMID 11854752. S2CID 10881911. Lu L, Hong W (September...

Retrieved 1 July 2015. "Protein sequence of human TPM2 (Uniprot ID: P07951-3)". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Archived from...

ADF/cofilin family: actin-remodeling proteins". Genome Biol. 3 (5) reviews3007. doi:10.1186/gb-2002-3-5-reviews3007. PMC 139363. PMID 12049672. Vartiainen MK...

Donowitz Mark (Jun 2002). "Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization...

incorporated into a schema. Nck1 is involved with cellular remodeling via the WASp/Arp2/3 complex to coordinate actin cytoskeletal remodeling. The WASp binds to the...

(skeletal muscle, slow), also known as TNN1 and SSTNI, is located at 1q31.3 in the human chromosomal genome, encoding the slow twitch skeletal muscle...

to the plasma membrane and regulates cell elasticity". FEBS Letters. 584 (3): 493–9. Bibcode:2010FEBSL.584..493O. doi:10.1016/j.febslet.2009.11.096. PMID 19968988...

(1997). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. Skowron JF, Bement WM,...

3. PMID 12054644. Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW (Jan 1984). "Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated...

R (January 2007). "IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway". J. Biol. Chem. 282 (1): 426–35. doi:10.1074/jbc.M607711200. PMID 17085436...

site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573. v...

interacting with ADAM19 cytoplasmic tail". Molecular Biology Reports. 29 (3): 317–323. doi:10.1023/A:1020409217215. PMID 12463424. S2CID 22611084. Kano...

(SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton"...

which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811. Puigvert A (1976). "Caliceal urodynamics"...

(SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton"...

et al. (2005). "Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement". J. Cell Sci. 118 (Pt 6): 1255–65. doi:10...

kinase act together to promote efficient cytokinesis". J. Cell Biol. 172 (3): 363–72. doi:10.1083/jcb.200511061. PMC 2063646. PMID 16431929. Corson TW...

glycoproteins, which is encoded by a 5.5 kb transcript in Homo sapiens on chromosome 3. There are two exons that are separated by a large intron. The spliced exons...

locus on chromosome 3, exclusion of candidate genes, and identification of the putative mouse homologous region". Genomics. 38 (3): 255–63. doi:10.1006/geno...

Cai L, Marshall TW, Uetrecht AC, et al. (2007). "Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge". Cell. 128 (5): 915–29...

"The Arp2/3 complex: A multifunctional actin organizer". Current Opinion in Cell Biology. 11 (1): 117–121. doi:10.1016/S0955-0674(99)80014-3. PMID 10047519...

1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. Swiatecka-Urban A, Talebian...

integrating cells into tissues". Physiological Reviews. 81 (3): 1353–92. doi:10.1152/physrev.2001.81.3.1353. PMID 11427698. S2CID 15307181. Kanzaki A, Rabodonirina...

protein-protein interaction domains". Biochem. Cell Biol. 76 (2–3): 351–8. doi:10.1139/bcb-76-2-3-351. PMID 9923704. Isomura T, Tamiya-Koizumi K, Suzuki M,...

Pericles, p. 178. Berlin, Altes Museum (Antikensammlung) F 2537. Beazley ARP2 1268, 2. See also A. Avramidou, The Codrus Painter: Iconography and Reception...

2020. Palmer, 1881, p. 293 Palmer, 1881, p. 306 Clermont-Ganneau, 1896, ARP2, p. 57 פסק-דין בתיק עש 2013/03 עברייני נדל"ן ודיירים מסתוריים: הכירו את שכונת...

"Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2". FEBS Letters. 402 (1): 57–61. doi:10.1016/S0014-5793(96)01500-1. PMID 9013859...

deaminase in patients with hyper IgM syndrome". Clinical Immunology. 97 (3). Orlando, Fla.: 203–210. doi:10.1006/clim.2000.4956. PMID 11112359. Simpson...

"Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2". FEBS Lett. 402 (1): 57–61. doi:10.1016/S0014-5793(96)01500-1. PMID 9013859...

angiopoietin-like gene expressed mainly in heart". Journal of Human Genetics. 48 (3): 159–162. doi:10.1007/s100380300025. PMID 12624729. Sun H, Zheng JM, Chen...

Microbiology and Immunology. Vol. 265. pp. 119–40. doi:10.1007/978-3-662-09525-6_6. ISBN 978-3-642-07655-8. PMID 12014186. Jefferis, Gregory SXE; Livet, Jean...