American sales did not live up to early expectations mainly due to customer disinterest in a mid-calorie soda; however, Coca-Cola said the brand would remain in its lineup, even while Pepsi discontinued its equivalent product, Pepsi Edge,[7] in late 2005, just one year after its introduction.[8]
By 2005, many store shelves completely replaced the product with Coca-Cola Zero due to display, shelving and storage limitations. The drink was silently discontinued in Japan in 2006 for similar reasons as in the United States, and by 2007 the drink had disappeared from all store shelves where it had previously remained in favor of Coca-Cola Cherry Zero.
In 2013, The Coca-Cola Company introduced a similar product - Coca-Cola Life, another mid-calorie variant of Coca-Cola which used Stevia leaf extract in addition to Sugar or Corn Syrup. Coca-Cola Life, while having had a larger availability rate than C2, shared similar low sales and was entirely discontinued by 2020.