DNAH11 (англ. Dynein axonemal heavy chain 11) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 7-ї хромосоми.[4] Довжина поліпептидного ланцюга білка становить 4 516 амінокислот, а молекулярна маса — 520 369[5].
Послідовність амінокислот
| 10 | | 20 | | 30 | | 40 | | 50 |
|---|
| MAAQVAAREA | | RDFREAPTLR | | LTSGAGLEAV | | GAVELEEEEE | | NEEEAAARRA |
| RSFAQDARVR | | FLGGRLAMML | | GFTEEKWSQY | | LESEDNRQVL | | GEFLESTSPA |
| CLVFSFAASG | | RLAASQEIPR | | DANHKLVFIS | | KKITESIGVN | | DFSQVVLFGE |
| LPALSLGHVS | | AFLDEILVPV | | LSNKNNHKSW | | SCFTSQDMEY | | HIEVMKKKMY |
| IFRGKMSRRT | | LLPIPTVAGK | | MDLDQNCSEN | | KPPSNERIIL | | HAIESVVIEW |
| SHQIQEIIER | | DSVQRLLNGL | | HLSPQAELDF | | WMMRRENLSC | | IYDQLQAPVV |
| LKMVKILTTK | | QSSYFPTLKD | | IFLAVENALL | | EAQDVELYLR | | PLRRHIQCLQ |
| ETEFPQTRIL | | IAPLFHTICL | | IWSHSKFYNT | | PARVIVLLQE | | FCNLFINQAT |
| AYLSPEDLLR | | GEIEESLEKV | | QVAVNILKTF | | KNSFFNYRKK | | LASYFMGRKL |
| RPWDFQSHLV | | FCRFDKFLDR | | LIKIEDIFAT | | TLEFEKLERL | | EFGGTKGAIL |
| NGQVHEMSEE | | LMELCKLFKQ | | STYDPSDCTN | | MEFESDYVAF | | KSKTLEFDRR |
| LGTIICEAFF | | NCNGLEAAFK | | LLTIFGNFLE | | KPVVMEIFSL | | HYSTLVHMFN |
| TELDVCKQLY | | NEHMKQIECG | | HVVLNKNMPF | | TSGNMKWAQQ | | VLQRLQMFWS |
| NFASLRYLFL | | GNPDHALVYQ | | KYVEMTTLLD | | QFESRIYNEW | | KSNVDEICEF |
| NLNQPLVKFS | | AINGLLCVNF | | DPKLVAVLRE | | VKYLLMLKKQ | | DIPDSALAIF |
| KKRNTILKYI | | GNLDLLVQGY | | NKLKQTLLEV | | EYPLIEDELR | | AIDEQLTAAT |
| TWLTWQDDCW | | GYIERVRAAT | | SELEHRVERT | | QKNVKVIQQT | | MRGWARCVLP |
| PRREHRREAA | | FTLEDKGDLF | | TKKYKLIQGD | | GCKIHNLVEE | | NRKLFKANPS |
| LDTWKIYVEF | | IDDIVVEGFF | | QAIMHDLDFF | | LKNTEKQLKP | | APFFQAQMIL |
| LPPEIVFKPS | | LDREAGDGFY | | DLVEEMLCNS | | FRMSAQMNRI | | ATHLEIKNYQ |
| NDMDNMLGLA | | EVRQEIMNRV | | VNVINKVLDF | | RNTLETHTYL | | WVDDRAEFMK |
| HFLLYGHAVS | | SDEMDAHANE | | EIPEQPPTLE | | QFKEQIDIYE | | ALYVQMSKFE |
| DFRVFDSWFK | | VDMKPFKVSL | | LTIIKKWSWM | | FQEHLLRFVI | | DSLNELQEFI |
| KETDSGLQRE | | LNEGDHDGLV | | DIMVHLLAVR | | SRQRATDELF | | EPLKETITLL |
| ESYGQKMPEQ | | VYIQLEELPE | | RWETTKKIAA | | TVRHEVSPLH | | NAEVTLIRKK |
| CILFDAKQAE | | FRERFRHYAP | | LGFNAENPYT | | ALDKANEELE | | ALEEEMLQMQ |
| ESTRLFEVAL | | PEYKQMKQCR | | KEIKLLKGLW | | DVIIYVRRSI | | DNWTKTQWRQ |
| IHVEQMDVEL | | RRFAKEIWSL | | NKEVRVWDAY | | TGLEGTVKDM | | TASLRAITEL |
| QSPALRDRHW | | HQLMKAIGVK | | FLINEATTLA | | DLLALRLHRV | | EDDVRRIVDK |
| AVKELGTEKV | | ITEISQTWAT | | MKFSYEVHYR | | TGIPLLKSDE | | QLFETLEHNQ |
| VQLQTLLQSK | | YVEYFIEQVL | | SWQNKLNIAD | | LVIFTWMEVQ | | RTWSHLESIF |
| VCSEDIRIQL | | VKDARRFDGV | | DAEFKELMFK | | TAKVENVLEA | | TCRPNLYEKL |
| KDLQSRLSLC | | EKALAEYLET | | KRIAFPRFYF | | VSSADLLDIL | | SKGAQPKQVT |
| CHLAKLFDSI | | ADLQFEDNQD | | VSAHRAVGMY | | SKEKEYVPFQ | | AECECVGHVE |
| TWLLQLEQTM | | QETVRHSITE | | AIVAYEEKPR | | ELWIFDFPAQ | | VALTSSQIWW |
| TTDVGIAFSR | | LEEGYETALK | | DFHKKQISQL | | NTLITLLLGE | | LPPGDRQKIM |
| TICTIDVHAR | | DVVAKLISQK | | VVSPQAFTWL | | SQLRHRWEDT | | QKHCFVNICD |
| AQFQYFYEYL | | GNSPRLVITP | | LTDRCYITLT | | QSLHLTMSGA | | PAGPAGTGKT |
| ETTKDLGRAL | | GMMVYVFNCS | | EQMDYKSIGN | | IYKGLVQTGA | | WGCFDEFNRI |
| SVEVLSVVAV | | QVKMIHDAIR | | NRKKRFVFLG | | EAITLKPSVG | | IFITMNPGYA |
| GRTELPENLK | | ALFRPCAMVA | | PDIELICEIL | | LVAEGFVDAR | | ALARKFITLY |
| TLCKELLSKQ | | DHYDWGLRAI | | KSVLVVAGSL | | KRGDKNRPED | | QVLMRALRDF |
| NMPKIVTDDI | | PVFLGLVGDL | | FPALDVPRRR | | KLHFEQMVRQ | | STLELRLQPE |
| ESFILKVVQL | | EELLAVRHSV | | FVVGNAGTGK | | SKILRTLNRT | | YVNMKQKPVW |
| NDLNPKAVTT | | DELFGFIHHA | | TREWKDGKIV | | YSYFIGLFSS | | ILREQANLKH |
| DGPKWIVLDG | | DIDPMWIESL | | NTVMDDNKVL | | TLASNERIAL | | TPFMRLLFEI |
| HHLRSATPAT | | VSRAGILYVN | | PQDLGWNPYV | | ASWIDRRRHQ | | SEKANLTILF |
| DKYVPACLDK | | LRTSFKTITS | | IPESSLVQTL | | CVLLECLLTP | | ENVPSDSPKE |
| VYEVYFVFAC | | IWAFGGTLLQ | | DQISDYQADF | | SRWWQKEMKA | | VKFPSQGTIF |
| DYYVDHKTKK | | LLPWADKIAQ | | FTMDPDVPLQ | | TVLVHTTETA | | RLRYFMELLL |
| EKGKPLMLVG | | NAGVGKTVFV | | GDTLASLSED | | YIVSRVPFNY | | YTTSTALQKI |
| LEKPLEKKAG | | HNYGPGGNKK | | LIYFIDDMNM | | PEVDLYGTVQ | | PHTLIRQHID |
| YGHWYDRQKV | | MLKEIHNCQY | | VACMNPMVGS | | FTINPRLQRH | | FTVFAFNFPS |
| LDALNTIYGQ | | IFSFHFQQQA | | FAPSILRSGP | | TLIQATIAFH | | QTMMCNFLPT |
| AIKFHYIFNL | | RDLSNVFQGI | | LFASPECLKG | | PLDLIHLWLH | | ESARVYGDKL |
| IDKKDCDLFQ | | RRMLETAYKY | | FEGIDSHMLL | | QQPLIYCHFA | | DRGKDPHYMP |
| VKDWEVLKTI | | LTETLDNYNE | | LNAAMHLVLF | | EDAMQHVCRI | | SRILRTPQGC |
| ALLVGVGGSG | | KQSLSRLAAY | | LRGLEVFQIT | | LTEGYGIQEL | | RVDLANLYIR |
| TGAKNMPTVF | | LLTDAQVLDE | | SFLVLINDLL | | ASGEIPDLFS | | DEDVDKIISG |
| IHNEVHALGM | | VDSRENCWKF | | FMARVRLQLK | | IILCFSPVGR | | TLRVRARKFP |
| AIVNCTAIDW | | FHAWPQEALV | | SVSRRFIEET | | KGIEPVHKDS | | ISLFMAHVHT |
| TVNEMSTRYY | | QNERRHNYTT | | PKSFLEQISL | | FKNLLKKKQN | | EVSEKKERLV |
| NGIQKLKTTA | | SQVGDLKARL | | ASQEAELQLR | | NHDAEALITK | | IGLQTEKVSR |
| EKTIADAEER | | KVTAIQTEVF | | QKQRECEADL | | LKAEPALVAA | | TAALNTLNRV |
| NLSELKAFPN | | PPIAVTNVTA | | AVMVLLAPRG | | RVPKDRSWKA | | AKVFMGKVDD |
| FLQALINYDK | | EHIPENCLKV | | VNEHYLKDPE | | FNPNLIRTKS | | FAAAGLCAWV |
| INIIKFYEVY | | CDVEPKRQAL | | AQANLELAAA | | TEKLEAIRKK | | LVDLDRNLSR |
| LTASFEKATA | | EKVRCQEEVN | | QTNKTIKLAN | | RLVKELEAKK | | IRWGQSIKSF |
| EAQEKTLCGD | | VLLTAAFVSY | | VGPFTRQYRQ | | ELVHCKWVPF | | LQQKVSIPLT |
| EGLDLISMLT | | DDATIAAWNN | | EGLPSDRMST | | ENAAILTHCE | | RWPLVIDPQQ |
| QGIKWIKNKY | | GMDLKVTHLG | | QKGFLNAIET | | ALAFGDVILI | | ENLEETIDPV |
| LDPLLGRNTI | | KKGKYIRIGD | | KECEFNKNFR | | LILHTKLANP | | HYKPELQAQT |
| TLLNFTVTED | | GLEAQLLAEV | | VSIERPDLEK | | LKLVLTKHQN | | DFKIELKYLE |
| DDLLLRLSAA | | EGSFLDDTKL | | VERLEATKTT | | VAEIEHKVIE | | AKENERKINE |
| ARECYRPVAA | | RASLLYFVIN | | DLQKINPLYQ | | FSLKAFNVLF | | HRAIEQADKV |
| EDMQGRISIL | | MESITHAVFL | | YTSQALFEKD | | KLTFLSQMAF | | QILLRKKEID |
| PLELDFLLRF | | TVEHTHLSPV | | DFLTSQSWSA | | IKAIAVMEEF | | RGIDRDVEGS |
| AKQWRKWVES | | ECPEKEKLPQ | | EWKKKSLIQK | | LILLRAMRPD | | RMTYALRNFV |
| EEKLGAKYVE | | RTRLDLVKAF | | EESSPATPIF | | FILSPGVDAL | | KDLEILGKRL |
| GFTIDSGKFH | | NVSLGQGQET | | VAEVALEKAS | | KGGHWVILQN | | VHLVAKWLGT |
| LEKLLERFSQ | | GSHRDYRVFM | | SAESAPTPDE | | HIIPQGLLEN | | SIKITNEPPT |
| GMLANLHAAL | | YNFDQDTLEI | | CSKEQEFKSI | | LFSLCYFHAC | | VAGRLRFGPQ |
| GWSRSYPFNP | | GDLTICASVL | | YNYLEANSKV | | PWEDLRYLFG | | EIMYGGHITD |
| DWDRKLCRVY | | LEEFMNPSLT | | EDELMLAPGF | | AAPPYLDYAG | | YHQYIEEMLP |
| PESPALYGLH | | PNAEIEFLTV | | TSNTLFRTLL | | EMQPRNALSG | | DELGQSTEEK |
| VKNVLDDILE | | KLPEEFNMAE | | IMQKNSNRSP | | YVLVCFQECE | | RMNILIREIR |
| ISLEQLDLSL | | KGELALSPAV | | EAQQFALSYD | | TVPDTWSKLA | | YPSTYGLAQW |
| FNDLLLRCRE | | LDTWTQDLTL | | PAVVWLSGFF | | NPQSFLTAIM | | QTMARKNEWP |
| LDKTRLTADV | | TKKTKEDYGH | | PPREGAYLHG | | LFMEGARWDT | | QAGTIVEARL |
| KELACPMPVI | | FAKATPVDRQ | | ETKQTYECPV | | YRTKLRGPSY | | IWTFRLKSEE |
| KTAKWVLAGV | | ALLLEA |
Кодований геном білок за функцією належить до білкових моторів.
Білок має сайт для зв'язування з АТФ, нуклеотидами.
Локалізований у цитоплазмі, цитоскелеті, клітинних відростках, війках.
Література
Примітки
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