PROFILBARU.COM

Toksiferin
Klinički podaci
Identifikatori
CAS broj	302-30-7
ATC kod	nije dodeljen
PubChem	5281411
ChemSpider	4444760
UNII	9M7D9K3OJI
ChEMBL	CHEMBL231047
Hemijski podaci
Formula	C40H46N4O2
Mol. masa	614,82 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C40H46N4O2/c1-43-15-13-39-31-7-3-5-9-33(31)41-22-30-28-20-36-40(14-16-44(36,2)24-26(28)12-18-46)32-8-4-6-10-34(32)42(38(30)40)21-29(37(39)41)27(19-35(39)43)25(23-43)11-17-45/h3-12,21-22,27-28,35-38,45-46H,13-20,23-24H2,1-2H3/b25-11-,26-12-,29-21-,30-22-/t27-,28-,35+,36+,37+,38+,39-,40+/m1/s1 ; Key: ZBADRGJKRGFNSR-IDJIJZEDSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Toksiferin je kurare toksin. On je antagonist nikotinskog acetilholinskog receptora.

On je mišićni relaksant koji uzrokuje paralizu skeletalnih mišića, koja traje oko dva sata pri umerenim dozama, i 8 sati totalne paralize pri dvadeset puta većoj dozi.^[5]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Page 330 in: The Alkaloids: v. 1: A Review of Chemical Literature (Specialist Periodical Reports). Cambridge, Eng: Royal Society of Chemistry. 1971. ISBN 0-85186-257-8.

Literatura

The Alkaloids: v. 1: A Review of Chemical Literature (Specialist Periodical Reports). Cambridge, Eng: Royal Society of Chemistry. 1971. ISBN 0-85186-257-8.