TNFSF8

944

TNFSF8
TNFSF8
Identifiers
AliasesTNFSF8, CD153, CD30L, CD30LG, TNLG3A, tumor necrosis factor superfamily member 8, TNF superfamily member 8
External IDsOMIM: 603875; MGI: 88328; GeneCards: TNFSF8
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

944

21949

Ensembl

ENSG00000106952

ENSMUSG00000028362

UniProt

P32971
Q52M88

P32972

RefSeq (mRNA)

NM_001252290
NM_001244

NM_009403

RefSeq (protein)

NP_001235
NP_001239219
NP_001235.1
NP_001239219.1

NP_033429

Location (UCSC)Chr 9: 114.89 – 114.93 MbChr 4: 63.75 – 63.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
tumor necrosis factor (ligand) superfamily, member 8
Identifiers
SymbolTNFSF8
Alt. symbolsCD30LG
NCBI gene944
HGNC11938
OMIM603875
RefSeqNM_001244
UniProtP32971
Other data
LocusChr. 9 q33
Search for
StructuresSwiss-model
DomainsInterPro

Tumor necrosis factor ligand superfamily member 8, also known as cluster of differentiation 153 (CD153), is a protein that in humans is encoded by the TNFSF8 gene.

CD153 is a cytokine ligand for the TNF receptor CD30. It plays a role in the T cell-dependent anti-mycobacterial immune response.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106952 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028362 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Marín ND, García LF (January 2017). "The role of CD30 and CD153 (CD30L) in the anti-mycobacterial immune response". Tuberculosis (Edinburgh, Scotland). 102: 8–15. doi:10.1016/j.tube.2016.10.006. PMID 28061955.


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