TAS2R39

TAS2R39
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GFZ
Identifiers
Aliases	TAS2R39, T2R39, T2R57, taste 2 receptor member 39
External IDs	MGI: 2681308; HomoloGene: 52214; GeneCards: TAS2R39; OMA:TAS2R39 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 143,183,419 bp[1] End 143,184,435 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B2.1 Start 42,117,870 bp[2] End 42,118,829 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle corpus callosum C1 segment Top expressed in embryo More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259285 353148 Ensembl ENSG00000236398 ENSMUSG00000047102 UniProt P59534 Q7TQA5 RefSeq (mRNA) NM_176881 NM_181275 RefSeq (protein) NP_795362 NP_851792 Location (UCSC) Chr 7: 143.18 – 143.18 Mb Chr 6: 42.12 – 42.12 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.^[5][6]

See also

• Taste receptor

References

1. GRCh38: Ensembl release 89: ENSG00000236398 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047102 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
6. "Entrez Gene: TAS2R39 taste receptor, type 2, member 39".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.