氟伏沙明

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氟伏沙明
臨床資料
懷孕分級
  • C
给药途径口服
ATC碼
法律規範狀態
法律規範
藥物動力學數據
生物利用度77%
药物代谢肝脏
生物半衰期20-23小时
排泄途徑肾脏
识别信息
  • (E)-2-[(5-methoxy-1- [4-(trifluoromethyl) phenyl]pentylidene) amino]oxyethanamine
CAS号54739-18-3  checkY
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
ECHA InfoCard100.125.476 編輯維基數據鏈接
化学信息
化学式C15H21F3N2O2
摩尔质量318.34 g·mol−1

氟伏沙明（Fluvoxamine）是一种选择性5-羟色胺再吸收抑制剂（SSRI）型的抗抑郁药，其药物形态为马来酸氟伏沙明（Fluvoxamine Maleate），商品名为“兰释”（Luvox）。在临床上常用于抑郁症及相关症状和强迫症的治疗。同时，兰释也可以治疗暴饮暴食症。

巴西的一项大型随机对照试验报告标明，在早期诊断为COVID-19的高风险门诊病人中，用氟伏沙明治疗减少了重病、住院的可能。[1]

参考资料

  1. ^ Reis G, dos Santos Moreira-Silva EA, Silva DC, Thabane L, Milagres AC, et al. Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial. The Lancet Global Health. 27 October 2021. ISSN 2214-109X. doi:10.1016/S2214-109X(21)00448-4. 

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