《古蘭經》的科學奇跡涉及宇宙創造、天文學、地理、生命起源及繁衍等科學。《古蘭經》提到太陽、地球等天體的形成是宇宙「混沌」通過融合和分離的過程而得,切合科學所指的星雲凝聚和坍縮,它描述的「七重天」亦符合宇宙的觀測結果。宇宙膨漲論(英语:Expansion of the universe)在現時是一種成熟的科學理論,通過對宇宙頻譜的觀測,這個理論在物理學獲得依據。它認為紅移導致星系距離的增加,因此宇宙的大小可能正在不斷膨漲,《古蘭經》有經文提及真主所創造的「天」正在擴大,切合這個理論的說法。另外,《古蘭經》對生命起源的說明非常明確,它提到真主「用水創造一切生物」,現代科學數據表明最古老的生物是植物,而稍後出現的動物也是來自海洋[42]。
有學者分析穆罕默德的言論,證明他的言論切合科學。舉例說,穆罕默德曾言除非阿拉伯再次變得青山綠水,否則復生日(英语:Day of Resurrection)不會到來,科學上通過對阿拉伯半島的分析證明,阿拉伯半島的確曾經是青山綠水之地。美國國家航空航天局的科學家透過衛星照片表示阿拉伯半島的沙漠曾經像歐洲一樣佈滿河流和湖泊。另外,穆罕默德又表示除了衰老,疾病皆可治療,許多科學家都證實衰老是人類最自然的死因,延年益壽引來許多副作用,包括癌症[參 1]。多人引述聖訓稱穆罕默德指人體有360個關節,儘管科學文獻基於人體年齡和對關節的定義存在分歧而沒有統計關節的數目,但作家扎格盧勒·納賈爾(英语:Zaghloul El-Naggar)認為他所指的是滑液關節,醫生哈米德·艾哈邁德·哈米德在他的著作裡經詳細計算指出人體關節正好有360個[47]。
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