Métmyoglobine

Cet article court présente un sujet plus développé dans : myoglobine.

La métmyoglobine est la forme oxydée de la myoglobine, une hémoprotéine abondante dans les muscles des mammifères. Elle est caractérisée par l'oxydation du cation de fer ferreux Fe2+ de l'hème b en fer ferrique Fe3+, ce qui donne une protéine de couleur brune, qui donne notamment sa couleur à la viande rouge vieillie. En revanche, la concentration en métmyoglobine demeure très faible dans le muscle vivant en raison de l'activité d'une enzyme, la métmyoglobine réductase, qui réduit le fer ferrique de la métmyoglobine en fer ferreux pour redonner de la myoglobine fonctionnelle en présence de cytochrome b5 et de NADH[1].

Notes et références

  1. ↑ (en) D. J. Livingston, S. J. McLachlan, G. N. La Mar et W. D. Brown, « Myoglobin: cytochrome b5 interactions and the kinetic mechanism of metmyoglobin reductase », Journal of Biological Chemistry, vol. 260, no 29,‎ , p. 15699-15707 (PMID 4066692, lire en ligne)

Liens externes

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Hémoprotéines et transporteurs d'oxygène
Hémoprotéines
Globines
Hémoglobines
Embryonnaires
Fœtales
Adultes
Hémoglobinopathies
Dérivées
Autres globines
Humaines
Végétales
Autres hémoprotéines
D'invertébrés
Autres fonctions
Transporteurs d'oxygène non héminiques

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