Clomegestone

Clomegestone

Identifiers
IUPAC name (1S,2R,10R,11S,13R,14R,15S)-14-acetyl-8-chloro-14-hydroxy-2,13,15-trimethyltetracyclo[8.7.0.0^2,7.0^11,15]heptadeca-6,8-dien-5-one
CAS Number	5367-84-0
PubChem CID	56840824
ChemSpider	32701810
UNII	ZHW74QJU5V
CompTox Dashboard (EPA)	DTXSID201023859
Chemical and physical data
Formula	C22H29ClO3
Molar mass	376.92 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1CC2C3C=C(C4=CC(=O)CCC4(C3CCC2(C1(C(=O)C)O)C)C)Cl
InChI InChI=1S/C22H29ClO3/c1-12-9-17-15-11-19(23)18-10-14(25)5-7-20(18,3)16(15)6-8-21(17,4)22(12,26)13(2)24/h10-12,15-17,26H,5-9H2,1-4H3/t12-,15-,16+,17+,20-,21+,22+/m1/s1 Key:GQBSINXSPAZDSK-ROXMKHFISA-N

Clomegestone (INN), or clomagestone, also known as 6-chloro-17α-hydroxy-16α-methylpregna-4,6-diene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.^[1][2] An acetate ester, clomegestone acetate, also exists, and similarly was never marketed.^[1]

References

1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 297–. ISBN 978-1-4757-2085-3.
2. World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 65, archived from the original (PDF) on August 8, 2016