11-Dehydroprogesterone, also known as pregna-4,11-diene-3,20-dione, is a steroidalprogestin that was never marketed.[1][2][3] It was found to be 2- to 3-fold as potent as progesterone as a progestogen in animalbioassays,[1][4] although other studies found them to be equivalent in potency.[2] 11-Dehydroprogesterone has been studied in women.[5] It was discovered in the 1930s or 1940s, and was one of the earliest synthetic progestogens.[3]
^ abZarrow MX, Neher GM, Lazowasem EA, Salhanick HA (May 1957). "Biological activity of certain progesterone-like compounds as determined by the Hooker-Forbes bioassay". The Journal of Clinical Endocrinology and Metabolism. 17 (5): 658–666. doi:10.1210/jcem-17-5-658. PMID13416376.