Kortikosteroid

Kortikosteroid
İlaç sınıfı
Kortizol (hidrokortizon), hem glukokortikoid hem de mineralokortikoid aktivitesi ve etkileri olan bir kortikosteroid.
Sınıf tanımlayıcıları
Diğer adlarKortikoid
KullanımVarious
ATC koduH02
Biyolojik hedefGlukokortikoid reseptörü, Mineralokortikoid reseptörü
Kimyasal sınıfSteroitler
Hukuki durum
Vikiveri

Kortikosteroid, böbrek üstü bezlerinde salgılanan bir steroid hormon türü ve bu hormonların sentetik analoglarına verilen addır. Glukokortikoid olan kortizon ile hidrokortizon kan şekeri seviyesi ve inflamasyon tepkisinde, mineralokortikoid olan aldosteron ise böbrek borucukları düzeyinde, su ve sodyumun geri emilimini ve potasyumun atılımını kolaylaştırarak su mineral dengesinde rol oynarlar.

Kullanım

Kortiosteroid ilaçlar Addison hastalığında ve adrenal bezler veya hipofiz bezi hastalıkta tahrip olduğunda ya da çıkarıldığında replasman (yerine koyma) tedavisi olarak kullanılırlar. Bu ilaçlar ayrıca ülseratif kolit, Crohn hastalığı gibi inflamatuvar bağırsak hastalıklarının tedavisinde ve temporal arteritte ortaya çıkan retinayı besleyen arterin inflamasyonunda acil tedavi için kullanılırlar.

Kortikosteroid ilaçların diğer kullanımları arasında sistemik lupus eritematosus (SLE) ve romatoid artrit gibi otoimmün hastalıkların tedavisi ve astım, egzama, alerjik rinit tedavisi de yer almaktadır. Kortikosteroid ilaçlar ayrıca transplant (organ nakli) cerrahisinden sonra organ reddini önlemek için ve lenfoma ve lösemi gibi kanser tedavilerinde de kullanılmaktadır. Ayrıca, tenisçi dirseği veya artrit gibi bozukluklarda ağrı giderici olarak da kortikosteroid injeksiyonları kullanılabilir. Kortikosteroidlerin antiinflamatuar (yangı önleyici) özellikleri vardır.

Sık kullanılan kortikosteroid ilaçlar aşağıda listelenmiştir:

Yan etkileri

47 yaşındaki bir kadının cildindeki topikal steroid hasarının sonuçları.

Kortikosteroid ilaçları krem yoluyla ya da inhaler olarak uygulandığında yan etkileri enderdir; ancak, uzun süre yüksek dozlarda alınan tabletler şeker hastalığı, hipertansiyon, osteoporoz, ödem, peptik ülser, Cushing sendromu, çocuklarda büyümeyi durdurma ve ender durumlarda katarakt ve psikoza neden olur.Yüksek dozda ilaç ayrıca immün sistemini de bozar ve septisemi ve tüberküloz gibi ciddi enfeksiyon riskini arttırır, kortikosteroid alan hastalarda suçiçeği yaşamı tehdit edici olabilir. Kortikosteroidlerin immun sistemi baskılayıcı özellikleri vardır.

Uzun dönemli tedavi adrenal bezlerinde kortikosteroid üretimini baskılayabilir ve ani bırakma yaşamı tehdit edici olan adrenal yetmezliğine neden olabilir. Bu nedenle, kortikosteroid almakta olan ya da kısa süre önce almış olan hastalarda br steroid tedavisi kartı olmalıdır ve herhangi bir tıbbi tedaviden önce doktorlar bu konuda bilgilendirilmelidir.

Kaynakça

  • BMA A-Z Family Medical Encyclopedia (British Medical Association A-Z Aile Tıp Ansiklopedisi)

Dış bağlantılar

Read other articles:

3 Mills Studios

3 Mills Studios 3 Mills Studios is a centre for film, television and theatre production near Stratford in East London. The site of a former distillery in Three Mills became a dedicated centre for television and film production work with the establishment in the 1980s of Bow Studios, Three Mills Island Studios, and Edwin Shirley Productions. In the mid-1990s, the three studios merged to become 3 Mills Studios, under the management of Workspace Group.[1] In August 2004, the London Devel...

 

Australians

Citizens of Australia This article is about people from Australia. For other uses, see Australian (disambiguation). This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Australians – news · newspapers · books · scholar · JSTOR (March 2023) (Learn how and when to remove this template message) AustraliansTotal popu...

 

Heino Hallhuber

Heino Hallhuber, 2003 Heino Hallhuber (bürgerlich Karlheinz Hallhuber) (* 16. Dezember 1927 in München; † 14. März 2021 in Hausham) war ein deutscher Tänzer, Choreograph und Schauspieler. Inhaltsverzeichnis 1 Leben 2 Filmografie (Auswahl) 3 Ehrungen 4 Weblinks 5 Einzelnachweise Leben Heino Hallhuber erhielt bereits als 9-Jähriger Ballettunterricht und wechselte später als Eleve an das Bayerische Staatsballett. Dort entwickelte er sich ab 1949 zu einem profilierten Solotänzer. 1957 ga...

Pengecoran cetakan pasir

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Oktober 2016. Pengecoran pasir, juga dikenal sebagai Pengecoran cetakan pasir, adalah proses pengecoran logam dengan menggunakan pasir sebagai bahan cetakan. Proses pengecoran meliputi: pembuatan cetakan, persiapan dan peleburan logam, penuangan logam cair ke dalam ...

 

List of United States Navy ships: S

USS Sacramento (AOE-1) Ships of the United States NavyShips in current service Current ships Ships grouped alphabetically A–B C D–F G–H I–K L M N–O P Q–R S T–V W–Z Ships grouped by type Aircraft carriers Airships Amphibious warfare ships Auxiliaries Battlecruisers Battleships Cruisers Destroyers Destroyer escorts Destroyer leaders Escort carriers Frigates Hospital ships Littoral combat ships Mine warfare vessels Monitors Oilers Patrol vessels Registered civilian vessels Sailin...

 

American immigration to Canada

Landing of the Loyalists in Canada American immigration to Canada was a notable part of the social history of Canada. Over Canada's history various refugees and economic migrants from the United States would immigrate to Canada for a variety of reasons. Exiled Loyalists from the United States first came, followed by African-American refugees (fugitive slaves), economic migrants, and later draft evaders from the Vietnam War. History Expulsion of the Loyalists Main article: Expulsion of the Loy...

Terminal Patria

Terminal PatriaTerminal Penumpang Tipe APapan Nama Terminal PatriaLokasiJalan Kenari Nomor 110, Rembang, Sananwetan, Kota Blitar, Jawa Timur 66135 IndonesiaKoordinat8°07′23″S 112°09′30″E / 8.123076°S 112.158281°E / -8.123076; 112.158281Koordinat: 8°07′23″S 112°09′30″E / 8.123076°S 112.158281°E / -8.123076; 112.158281Pemilik Pemerintah Kota BlitarPengelola Kementerian Perhubungan Republik IndonesiaJalurJalan Nasional ...

 

City of the Iron Fish

1994 novel by Simon Ings City of the Iron Fish First UK edition coverAuthorSimon IngsCountryUnited KingdomLanguageEnglishGenreFantasy novelPublisherHarperCollinsPublication date1994Media typePrint (paperback original, e-book)Pages314ISBN978-0-00-647653-5 City of the Iron Fish is a fantasy novel by English science fiction and fantasy author Simon Ings. It was first published in July 1994 in the United Kingdom as a paperback original by HarperCollins. The book is about an isolated city bou...

 

Madame Dares an Escapade

1927 film Madame Dares an EscapadeLivio Pavanelli and Betty BirdDirected byHans OttoWritten byHans OttoStarringXenia DesniLivio PavanelliCarmen CartellieriCinematographyWalter WeißeProductioncompanyDomo-Strauß-FilmDistributed byDomo-Strauß-FilmRelease dateJune 1927CountryGermanyLanguagesSilent German intertitles Madame Dares an Escapade (German: Madame wagt einen Seitensprung) is a 1927 German silent film directed by Hans Otto and starring Xenia Desni, Livio Pavanelli and Carmen Cartellier...

Suku Tomini

Artikel ini perlu diwikifikasi agar memenuhi standar kualitas Wikipedia. Anda dapat memberikan bantuan berupa penambahan pranala dalam, atau dengan merapikan tata letak dari artikel ini. Untuk keterangan lebih lanjut, klik [tampil] di bagian kanan. Mengganti markah HTML dengan markah wiki bila dimungkinkan. Tambahkan pranala wiki. Bila dirasa perlu, buatlah pautan ke artikel wiki lainnya dengan cara menambahkan [[ dan ]] pada kata yang bersangkutan (lihat WP:LINK untuk keterangan lebih lanjut...

 

Percent sign

Math symbol (%) (Parts per hundred.) % redirects here. For the mod sign as used in modular arithmetic, see Modular arithmetic. %Percent signIn UnicodeU+0025 % PERCENT SIGN (%)Different fromDifferent fromU+2052 ⁒ COMMERCIAL MINUS SIGNU+00F7 ÷ DIVISION SIGNRelatedSee alsoU+2030 ‰ PER MILLE SIGNU+2031 ‱ PER TEN THOUSAND SIGN (Basis point) The percent sign % (sometimes per cent sign in British English) is the symbol used to i...

 

UFC 36

UFC mixed martial arts event in 2002 UFC 36: Worlds CollideThe poster for UFC 36: Worlds CollideInformationPromotionUltimate Fighting ChampionshipDateMarch 22, 2002VenueMGM Grand ArenaCityLas Vegas, NevadaAttendance10,000[1]Total gate$898,850[1]Buyrate55,000[1]Event chronology UFC 35: Throwdown UFC 36: Worlds Collide UFC 37: High Impact UFC 36: Worlds Collide was a mixed martial arts event held by the Ultimate Fighting Championship at the MGM Grand Arena in Las Vegas, ...

Carex media

Carex media Klasifikasi ilmiah Kerajaan: Plantae Divisi: Tracheophyta Kelas: Liliopsida Ordo: Poales Famili: Cyperaceae Genus: Carex Spesies: Carex media Nama binomial Carex mediaR.Br. Carex media adalah spesies tumbuhan seperti rumput yang tergolong ke dalam famili Cyperaceae. Spesies ini juga merupakan bagian dari ordo Poales. Spesies Carex media sendiri merupakan bagian dari genus Carex.[1] Nama ilmiah dari spesies ini pertama kali diterbitkan oleh R.Br.. Referensi ^ Carex. The Pla...

 

Gamba Osaka

Gamba Osakaガンバ大阪Nama lengkapGamba OsakaBerdiri1980 (asli)1991 (Gamba Osaka)StadionStadion Kota Suita, Suita, Osaka(Kapasitas: 40,000)Pemilik PanasonicPresiden Takashi YamauchiManajer Tsuneyasu MiyamotoLigaJ1 League2022ke-15Situs webSitus web resmi klub Kostum kandang Kostum tandang Gamba Osaka (ガンバ大阪code: ja is deprecated ) merupakan klub sepak bola Jepang yang bermain di divisi satu J-League. Tim ini bermarkas di Suita, Prefektur Osaka, Jepang. Didirikan pada tahun 1...

 

The Fields Bar and Grill

Sports bar and restaurant in Portland, Oregon, U.S. The Fields Bar and GrillThe restaurant's exterior, 2023Restaurant informationFood typeAmericanStreet address1139 Northwest 11th AvenueCityPortlandCountyMultnomahStateOregonPostal/ZIP Code97209CountryUnited StatesCoordinates45°31′53″N 122°40′57″W / 45.5313°N 122.6826°W / 45.5313; -122.6826Websitethefieldspdx.com The Fields Bar and Grill is a sports bar and restaurant in Portland, Oregon's Pearl District, in...

North Troy, Vermont

Village in Vermont, United StatesNorth Troy, VermontVillageNorth Troy, VermontLocation within the state of VermontCoordinates: 44°59′41″N 72°24′2″W / 44.99472°N 72.40056°W / 44.99472; -72.40056CountryUnited StatesStateVermontCountyOrleansArea[1] • Total1.92 sq mi (4.97 km2) • Land1.87 sq mi (4.85 km2) • Water0.04 sq mi (0.12 km2)Elevation561 ft (171 m)Populati...

 

Тайваньская опера

Тайваньская опера Тайваньская опера (歌仔戲,Тайваньский язык :Гуа-а Хи) — форма традиционной китайской драмы, имеет тайваньское происхождение, зародилась в уезде Илан в конце XIX в. История В середине XIX века переселенцы из Китая объединили свои песни и танцы с народ...

 

Alex MacDowall

British racing driver (born 1991) Alex MacDowallAlex MacDowall Racing Driver in 2014Nationality BritishBorn (1991-01-22) 22 January 1991 (age 32)Carlisle (England)FIA World Endurance Championship careerDebut season2014Current teamAston Martin RacingCar number99Starts15Wins1Poles4Fastest laps1Best finish7th in 2015Previous series20132010–201120092007–200920072005–2006World Touring Car ChampionshipGinetta GT SupercupBritish Touring Car ChampionshipSpanish SEAT SupercopaRenault Clio C...

Nicolás Aleksándrovich de Rusia

Nicolás Aleksándrovich Románov Zarévich y gran duque de Rusia Información personalNombre completo Nicolás Aleksándrovich Románov (en ruso: Николай Алекса́ндрович Рома́нов)Nacimiento 20 de septiembre de 1843Palacio de Alejandro, Gubérniya de San Petersburgo,  Imperio rusoFallecimiento 24 de abril de 1865(21 años)Niza, FranciaSepultura Catedral de San Pedro y San Pablo de San PetersburgoReligión Cristiano ortodoxoFamiliaDinastía Románov-Holstein-Go...

 

Wolfsbane (album)

This article is about the album. For other uses, see Wolfsbane (disambiguation). This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Wolfsbane album – news · newspapers · books · scholar · JSTOR (December 2009) (Learn how and when to remove this template message) 1994 studio album by WolfsbaneWolfsbaneS...

 

Strategi Solo vs Squad di Free Fire: Cara Menang Mudah!