Dr. Andrew Manson (Robert Donat) is an idealistic, newly qualified Scottish doctor dedicated to treating the Welsh miners suffering from tuberculosis in the Welsh mining village of Blaenely and is an apprentice to Dr. Page (Basil Gill). Initially, he has many lofty scientific goals, but meets local resistance in his research. After his laboratory and notes are destroyed by the miners, he moves to London, treating working-class patients in impoverished conditions. There, his purpose erodes when a chance encounter with a medical school friend, Dr. Frederick Lawford (Rex Harrison) leads to his quiet seduction by an unethical medical establishment, treating rich hypochondriacs. Christine (Rosalind Russell), his wife, tries to set him back on the original path. Dr. Philip Denny (Ralph Richardson), Manson's best friend and still working for improved working-class health, dies at the hands of an incompetent, social-climbing surgeon.
Differences from other versions
The film is based on the novel, but departs from it in certain vital respects. In the original text, the character of Christine Manson is killed off in a road accident at the point when she and her husband have begun to address problems in their relationship. The incident involving the incompetent surgeon occurs, but it is a minor character who dies. Denny survives, and the understanding (not related in the book but implied) is that he and Manson went into practice together.[3] A 1982 BBC radio adaptation[4] of the novel stays closer to the original text.