SSBP4

SSBP4
Identifiers
Aliases	SSBP4, single stranded DNA binding protein 4
External IDs	OMIM: 607391; MGI: 1924150; HomoloGene: 41881; GeneCards: SSBP4; OMA:SSBP4 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.11 Start 18,418,864 bp[1] End 18,434,562 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.3 Start 70,597,490 bp[2] End 70,608,872 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube anterior pituitary granulocyte canal of the cervix left uterine tube right frontal lobe caudate nucleus nucleus accumbens body of uterus right ovary Top expressed in neural layer of retina superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex entorhinal cortex perirhinal cortex ventricular zone olfactory tubercle ankle joint subiculum More reference expression data BioGPS n/a
Gene ontology Molecular function single-stranded DNA binding DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific protein binding Cellular component nucleus Biological process transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 170463 76900 Ensembl ENSG00000130511 ENSMUSG00000070003 UniProt Q9BWG4 n/a RefSeq (mRNA) NM_001009998 NM_032627 NM_133772 RefSeq (protein) NP_001009998 NP_116016 n/a Location (UCSC) Chr 19: 18.42 – 18.43 Mb Chr 8: 70.6 – 70.61 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Single-stranded DNA-binding protein 4 is a protein that in humans is encoded by the SSBP4 gene.^[5][6]

References

1. GRCh38: Ensembl release 89: ENSG00000130511 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000070003 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Castro P, Liang H, Liang JC, Nagarajan L (July 2002). "A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity". Genomics. 80 (1): 78–85. doi:10.1006/geno.2002.6805. PMID 12079286.
6. "SSBP4 - Single-stranded DNA-binding protein 4 - Homo sapiens (Human) - SSBP4 gene & protein". www.uniprot.org. Retrieved 2019-01-23.

Further reading

• Guo X, et al. (May 2018). "A Comprehensive cis-eQTL Analysis Revealed Target Genes in Breast Cancer Susceptibility Loci Identified in Genome-wide Association Studies". American Journal of Human Genetics. 102 (5): 890–903. doi:10.1016/j.ajhg.2018.03.016. PMC 5986971. PMID 29727689.