Pacrinolol

Pacrinolol
Names
IUPAC name
(E)-3-[4-[3-[2-(3,4-Dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]phenyl]but-2-enenitrile
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C23H28N2O4/c1-17(10-12-24)19-5-7-21(8-6-19)29-16-20(26)15-25-13-11-18-4-9-22(27-2)23(14-18)28-3/h4-10,14,20,25-26H,11,13,15-16H2,1-3H3/b17-10+
    Key: BMAJJBHGPUHERB-LICLKQGHSA-N
  • InChI=1/C23H28N2O4/c1-17(10-12-24)19-5-7-21(8-6-19)29-16-20(26)15-25-13-11-18-4-9-22(27-2)23(14-18)28-3/h4-10,14,20,25-26H,11,13,15-16H2,1-3H3/b17-10+
    Key: BMAJJBHGPUHERB-LICLKQGHBO
  • N#C\C=C(\c2ccc(OCC(O)CNCCc1cc(OC)c(OC)cc1)cc2)C
  • C/C(=C\C#N)/C1=CC=C(C=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O
Properties
C23H28N2O4
Molar mass 396.487 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Pacrinolol is a beta adrenergic receptor antagonist.[1]

References

  1. ^ Stache, U; Fritsch, W; Fehlhaber, HW (1987). "Synthesis of the highly cardioselective beta-sympatholytic pacrinolol". Arzneimittel-Forschung. 37 (11): 1217–21. PMID 2894210.


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