Аполіпопротеїн L6

APOL6
Ідентифікатори
Символи APOL6, APOL-VI, APOLVI, apolipoprotein L6
Зовнішні ІД OMIM: 607256 MGI: 1919189 HomoloGene: 49940 GeneCards: APOL6
Шаблон експресії
Більше даних
Ортологи
Види Людина Миша
Entrez
Ensembl
UniProt
RefSeq (мРНК)
NM_030641
NM_001163621
NM_028010
RefSeq (білок)
NP_085144
н/д
Локус (UCSC) Хр. 22: 35.65 – 35.67 Mb Хр. 15: 76.93 – 76.94 Mb
PubMed search [1] [2]
Вікідані
Див./Ред. для людейДив./Ред. для мишей

APOL6 (англ. Apolipoprotein L6) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 22-ї хромосоми.[3] Довжина поліпептидного ланцюга білка становить 343 амінокислот, а молекулярна маса — 38 128[4].

Послідовність амінокислот
1020304050
MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLK
EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAP
ATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYD
QEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANA
TKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLA
TLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRA
RGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT

Задіяний у таких біологічних процесах, як транспорт, транспорт ліпідів. Локалізований у цитоплазмі.

Література

  • Page N.M., Butlin D.J., Lomthaisong K., Lowry P.J. (2001). The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. Genomics. 74: 71—78. PMID 11374903 doi:10.1006/geno.2001.6534
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14: 2121—2127. 2004. PMID 15489334 doi:10.1101/gr.2596504

Примітки

  1. Human PubMed Reference:.
  2. Mouse PubMed Reference:.
  3. HUGO Gene Nomenclature Commitee, HGNC:14870 (англ.) . Процитовано 12 вересня 2017.{{cite web}}: Обслуговування CS1: Сторінки з параметром url-status, але без параметра archive-url (посилання)
  4. UniProt, Q9BWW8 (англ.) . Архів оригіналу за 26 лютого 2018. Процитовано 12 вересня 2017.

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