Metilmalonil-KoA mutaza

Metilmalonil-KoA mutaza
Identifikatori
EC broj	5.4.99.2
CAS broj	9023-90-9
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Metilmalonil-KoA mutaza (EC 5.4.99.2, metilmalonil-KoA KoA-karbonil mutaza, metilmalonil koenzim A mutaza, metilmalonil koenzim A karbonilmutaza, (S)-metilmalonil-KoA mutaza, (R)-2-metil-3-oksopropanoil-KoA KoA-karbonilmutaza) je enzim sa sistematskim imenom (R)-metilmalonil-KoA KoA-karbonilmutaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

(R)-metilmalonil-KoA ${\displaystyle \rightleftharpoons }$ sukcinil-KoA

Za dejstvo ovog enzima je neophodan kobamidni koenzim.

Reference

1. Barker, H.A. (1972). „Coenzyme B₁₂-dependent mutases causing carbon chain rearrangements”. u: Boyer, P.D.. The Enzymes. 6 (3rd izd.). New York: Academic Press. str. 509-537. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

• Barker, H.A. (1972). „Coenzyme B₁₂-dependent mutases causing carbon chain rearrangements”. u: Boyer, P.D.. The Enzymes. 6 (3rd izd.). New York: Academic Press. str. 509-537. 

Spoljašnje veze

• MeSH Methylmalonyl-CoA+mutase