Manoza-1-fosfat guanililtransferaza

Manoza-1-fosfat guanililtransferaza
Identifikatori
EC broj	2.7.7.13
CAS broj	37278-24-3
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Manoza-1-fosfat guanililtransferaza (EC 2.7.7.13, GTP-manoza-1-fosfat guanililtransferaza, PIM-GMP (fosfomanoza izomeraza-guanozin 5'-difosfo-D-manoza pirofosforilaza), GDP-manoza pirofosforilaza, guanozin 5'-difosfo-D-manoza pirofosforilaza, guanozin difosfomanoza pirofosforilaza, guanozin trifosfat-manoza 1-fosfat guanililtransferaza, manoza 1-fosfat guanililtransferaza (guanozin trifosfat)) je enzim sa sistematskim imenom GTP:alfa-D-manoza-1-fosfat guanililtransferaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

GTP + alfa-D-manoza 1-fosfat ${\displaystyle \rightleftharpoons }$ difosfat + GDP-manoza

Bakterijski enzim takođe može da koristi ITP i dGTP kao donore.

Reference

1. Munch-Peterson, A. (1955). „Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose”. Arch. Biochem. Biophys. 55: 592-593. 
2. Preiss, J. and Wood, E. (1964). „Sugar nucleotide reactions in Arthrobacter. I. Guanosinediphosphate mannose pyrophosphorylase: purification and properties”. J. Biol. Chem. 239: 3119-3126. PMID 14245350. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Mannose-1-phosphate+guanylyltransferase