Hinat O-hidroksicinamoiltransferaza

Hinat O-hidroksicinamoiltransferaza
Identifikatori
EC broj	2.3.1.99
CAS broj	60321-02-0
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Hinat O-hidroksicinamoiltransferaza (EC 2.3.1.99, hidroksicinamoil koenzim A-hinat transferaza) je enzim sa sistematskim imenom feruloil-KoA:hinat O-(hidroksicinamoil)transferaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:

feruloil-KoA + hinat ${\displaystyle \rightleftharpoons }$ KoA + O-feruloilhinat

Kofeoil-KoA i 4-kumaroil-KoA takođe mogu da deluju kao donori, mada sporije. Ovaj enzim učestvuje u biosintezi hlorogene kiseline u slatkom krompiru, i sa enzimom EC 2.3.1.98, hlorogenat---glukarat O-hidroksicinamoiltransferaza, u formiranju kafeoil-KoA u paradajzu.

Reference

1. Strack, D., Gross, W., Wray, V. and Grotjahn, L. (1987). „Enzymatic-synthesis of caffeoylglucaric acid from chlorogenic acid and glucaric acid by a protein preparation from tomato cotyledons”. Plant Physiol. 83: 475-478. PMID 16665274. 
2. Strack, D., Keller, H. and Weissenböck, G. (1987). „Enzymatic-synthesis of hydroxycinnamic acid-esters of sugar acids and hydroaromatic acids by protein preparations from rye (Secale cereale) primary leaves”. J. Plant Physiol. 131: 61-73. 
3. Villegas, R.J.A. and Kojima, M. (1986). „Purification and characterization of hydroxycinnamoyl D-glucose. Quinate hydroxycinnamoyl transferase in the root of sweet potato, Ipomoea batatas Lam”. J. Biol. Chem. 261: 8729-8733. PMID 3722170. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Quinate+O-hydroxycinnamoyltransferase