Beta-litička metaloendopeptidaza

Beta-litička metaloendopeptidaza
Identifikatori
EC broj	3.4.24.32
CAS broj	37288-92-9
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Beta-litička metaloendopeptidaza (EC 3.4.24.32, Myxobacter beta-litička proteinaza, ahromopeptidazna komponenta, beta-litička metaloproteinaza, beta-litička proteaza, Myxobakterija sorangium beta-litička proteinaza, Myxobacter495 beta-litička proteinaza) je enzim.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje N-acetilmuramoil-Ala}, i lanca insulina B u Gly²³-Phe > Val¹⁸-Cys

Ovaj ezim je prisutan u Achromobacter lyticus i Lysobacter enzymogenes.

Reference

1. Whitaker, D.R., Roy, C., Tsai, C.S. and Juraöek, L. (1965). „Lytic enzymes of Sorangium sp. A comparison of the proteolytic properties of the α- and β-lytic proteases”. Can. J. Biochem. 43: 1961-1970. PMID 5880182. 
2. Whitaker, D.R. and Roy, C. (1967). „Concerning the nature of the α- and β-lytic proteases of Sorangium sp”. Can. J. Biochem. 45: 911-911. PMID 6034704. 
3. Li, S. (1990). „L., Norioka, S. and Sakiyama, F. Molecular cloning and nucleotide sequence of the β-lytic protease gene from Achromobacter lyticus”. J. Bacteriol. 172: 6506-6511. PMID 2228973. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Beta-lytic+metalloendopeptidase