3-Merkaptopiruvat sumportransferaza

3-merkaptopiruvat sumportransferaza
Identifikatori
EC broj	2.8.1.2
CAS broj	2602844
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

3-merkaptopiruvat sumportransferaza (EC 2.8.1.2, beta-merkaptopiruvatna sumportransferaza) je enzim sa sistematskim imenom 3-merkaptopiruvat:cijanid sumportransferaza.^{[1][2][3][4][5]} Ovaj enzim katalizuje sledeću hemijsku reakciju

3-merkaptopiruvat + cijanid ${\displaystyle \rightleftharpoons }$ piruvat + tiocijanat

Sulfit, sulfinati, merkaptoetanol i merkaptopiruvat takođe mogu da deluju kao akceptori.

Reference

1. Fiedler, H. and Wood, J.L. (1956). „Specificity studies on the β-mercaptopyruvate-cyanide transsulfuration system”. J. Biol. Chem. 222: 387-397. PMID 13367011. 
2. Hylin, J.W. and Wood, J.L. (1959). „Enzymatic formation of polysulfides from mercaptopyruvate”. J. Biol. Chem. 234: 2141-2144. PMID 13673028. 
3. Sörbo, B.H. (1957). „Enzymic transfer of sulfur from mercaptopyruvate to sulfite or sulfinates”. Biochem. Biophys. Acta 24: 324-329. PMID 13436433. 
4. Vachek, H. and Wood, J.L. (1972). „Purification and properties of mercaptopyruvate sulfur transferase of Escherichia coli”. Biochim. Biophys. Acta 258: 133-146. PMID 4550801. 
5. van den Hamer, C.J.A., Morell, A.G. and Scheinberg, H.I. (1967). „A study of the copper content of β-mercaptopyruvate trans-sulfurase”. J. Biol. Chem. 242: 2514-2516. PMID 6026243. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH 3-mercaptopyruvate+sulfurtransferase