Вориконазол

Вориконазол
Изображение химической структуры
Изображение химической структуры
Химическое соединение
ИЮПАК (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Брутто-формула C16H14F3N5O
Молярная масса 349.311 г/моль
CAS 137234-62-9
PubChem 71616
DrugBank DB00582
Состав
Классификация
АТХ J02AC03
Фармакокинетика
Биодоступн. 96%
Связывание с белками плазмы 58%
Метаболизм Hepatic cytochrome P450 enzymes CYP2C19, CYP2C9, CYP3A4
Период полувывед. Dose-dependent
Способы введения
IV, oral
Другие названия
VFEND (Вифенд), Виканд, Бифлурин
Логотип Викисклада Медиафайлы на Викискладе
Vfend 200 мг

Вориконазол — синтетический противогрибковый препарат группы триазолов. Одобрен для применения: США(2002)[1], Россия[2].

Показания

Для пациентов с 12 лет[3]:

Примечания

  1. ↑ NME Drug and New Biologic Approvals in 2002 (англ.). FDA. Дата обращения: 13 апреля 2020. Архивировано 6 апреля 2017 года.
  2. ↑ Регистрационное удостоверение. Государственный реестр лекарственных средств.
  3. ↑ VFEND- voriconazole tablet, film coated VFEND- voriconazole injection, powder, lyophilized, for solution VFEND- voriconazole powder, for suspension (англ.). DailyMed. U. S. National Library of Medicine.

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