Taurine—2-oxoglutarate transaminase

taurine-2-oxoglutarate transaminase
Identifiers
EC no.	2.6.1.55
CAS no.	9076-52-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a taurine-2-oxoglutarate transaminase (EC 2.6.1.55) is an enzyme that catalyzes the chemical reaction.

taurine + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ sulfoacetaldehyde + L-glutamate

Thus, the two substrates of this enzyme are taurine and 2-oxoglutarate, whereas its two products are sulfoacetaldehyde and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:2-oxoglutarate aminotransferase. Other names in common use include taurine aminotransferase, taurine transaminase, taurine-alpha-ketoglutarate aminotransferase, and taurine-glutamate transaminase. This enzyme participates in beta-alanine metabolism. It employs one cofactor, pyridoxal phosphate.

References

• Toyama S, Misono H, Soda K (1972). "Crystalline taurine: -ketoglutarate aminotransferase from Achromobacter superficialis". Biochem. Biophys. Res. Commun. 46 (3): 1374–9. doi:10.1016/S0006-291X(72)80127-X. PMID 5012173.
• Cook AM, Denger K (2002). "Dissimilation of the C2 sulfonates". Arch. Microbiol. 179 (1): 1–6. doi:10.1007/s00203-002-0497-0. PMID 12471498.