Sulfoacetaldehyde dehydrogenase (acylating)

Sulfoacetaldehyde dehydrogenase (acylating)
Identifiers
EC no.	1.2.1.81
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Sulfoacetaldehyde dehydrogenase (acylating) (EC 1.2.1.81, SauS) is an enzyme with systematic name 2-sulfoacetaldehyde:NADP⁺ oxidoreductase (CoA-acetylating).^[1] This enzyme catalyses the following chemical reaction

2-sulfoacetaldehyde + CoA + NADP⁺ ${\displaystyle \rightleftharpoons }$ sulfoacetyl-CoA + NADPH + H⁺

The enzyme is involved in degradation of sulfoacetate.

References

1. Weinitschke S, Hollemeyer K, Kusian B, Bowien B, Smits TH, Cook AM (November 2010). "Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16". The Journal of Biological Chemistry. 285 (46): 35249–54. doi:10.1074/jbc.M110.127043. PMC 2975148. PMID 20693281.

External links

• Sulfoacetaldehyde+dehydrogenase+(acylating) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)