Nicotine blue oxidoreductase

Nicotine blue oxidoreductase
Identifiers
EC no.	1.1.1.328
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Nicotine blue oxidoreductase (EC 1.1.1.328, nboR (gene)) is an enzyme with systematic name 3,3'-bipyridine-2,2',5,5',6,6'-hexol:NADP⁺ 11-oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(P)⁺ ${\displaystyle \rightleftharpoons }$ (E)-2,2',5,5'-tetrahydroxy-6H,6'H-[3,3'-bipyridinylidene]-6,6'-dione + NAD(P)H + H⁺

This enzyme is extracted from bacterium Arthrobacter nicotinovorans.

References

1. Mihasan M, Chiribau CB, Friedrich T, Artenie V, Brandsch R (April 2007). "An NAD(P)H-nicotine blue oxidoreductase is part of the nicotine regulon and may protect Arthrobacter nicotinovorans from oxidative stress during nicotine catabolism". Applied and Environmental Microbiology. 73 (8): 2479–85. doi:10.1128/AEM.02668-06. PMC 1855579. PMID 17293530.

External links

• Nicotine+blue+oxidoreductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)