His personal best for the 800 m was 1:42.86 minutes. He ranked first on time in the 2006 and 2007 seasons, becoming the first Black South African to achieve such a feat.[3]
Mulaudzi died in a car crash on 24 October 2014 at the age of 34.[12] He was en route to an Athletics South Africa athletics meeting when his car overturned.[13][14] His death was confirmed by his manager, Peet van Zyl, who said: "Mr Mulaudzi was surely one of the most decorated track athletes that South Africa has ever seen and unfortunately never had the recognition from the federation for all his achievements, so it is indeed a sad day."[15] The President of South Africa, Jacob Zuma, noted his death, saying that he was one of the nation's most talented athletes. Presidential spokesperson Mac Maharaj mirrored this, saying that the nation had lost a hero and that Mulaudzi had flown the South African flag through his athletics.[13] The International Association of Athletics Federations, the governing body for the sport, said it was "deeply saddened" to hear of Mulaudzi's death.[16] The International Olympic Committee expressed sadness and sympathy towards the sports family of South Africa and Mulaudzi's friends and family.[17] South African athletes Caster Semenya and Khotso Mokoena used Twitter to express their emotions following Mulaudzi's death. Semenya said: "Just lost a brother, a friend very good friend! May your soul rest in peace Mbulayeni Mulaudzi! I love you man will always love you Champ!" and Mokoena said: "I've lost a brother, a friend, and a national hero! Sad news to my soul..."[18]