From 1942 to 1946 served as a pilot in the Tuskegee Airmen.[1] Wise's plane was shot down over Romania near the Ploesti oilfields. He spent three months as a prisoner of war.[3]
In 1955 Wise left his family practice to work as a physician at Prince George's Hospital Center. At that time Wise was the only African American physician. He went on to become the medical director at Bowie State University[3]
^The red markings that distinguished the Tuskegee Airmen included red bands on the noses of P-51s as well as a red rudder; their P-51B and D Mustangs flew with similar color schemes, with red propeller spinners, yellow wing bands and all-red tail surfaces.[2]