Farnesol dehydrogenase

farnesol dehydrogenase
Identifiers
EC no.	1.1.1.216
CAS no.	90804-55-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a farnesol dehydrogenase (EC 1.1.1.216) is an enzyme that catalyzes the chemical reaction

2-trans,6-trans-farnesol + NADP⁺ ${\displaystyle \rightleftharpoons }$ 2-trans,6-trans-farnesal + NADPH + H⁺

Thus, the two substrates of this enzyme are 2-trans,6-trans-farnesol and NADP⁺, whereas its 3 products are 2-trans,6-trans-farnesal, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 2-trans,6-trans-farnesol:NADP⁺ 1-oxidoreductase. Other names in common use include NADP⁺-farnesol dehydrogenase, and farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase.

References

• Inoue H, Tsuji H, Uritani I (1984). "Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato". Agric. Biol. Chem. 48 (3): 733–738. doi:10.1271/bbb1961.48.733.