Citiolone

Citiolone
Clinical data
ATC code	A05BA04 (WHO) ;
Identifiers
	IUPAC name (RS)-N-(2-Oxothiolan-3-yl)acetamide;
CAS Number	1195-16-0 ;
PubChem CID	14520;
ChemSpider	13864 ;
UNII	70JKL15MUH;
KEGG	D07105 ;
ChEMBL	ChEMBL2104457 ;
CompTox Dashboard (EPA)	DTXSID0045888 ;
ECHA InfoCard	100.013.449
Chemical and physical data
Formula	C6H9NO2S
Molar mass	159.20 g·mol−1
	InChI InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) ; Key:NRFJZTXWLKPZAV-UHFFFAOYSA-N ;
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Citiolone is a drug used in liver therapy.

It is a derivative of the amino acid cysteine.^[1] Citilone has also been studied with regards to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25 °C.^[2]

References

^ de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone". Journal of Investigational Allergology & Clinical Immunology. 7 (3): 193–194. PMID 9252880.
^ Kruuv J, Glofcheski DJ (June 1993). "Further evidence for two modes of hypothermia damage". Cryobiology. 30 (3): 313–321. doi:10.1006/cryo.1993.1030. PMID 8370318.