3-hydroxybenzoate—CoA ligase

3-Hydroxybenzoate—CoA ligase
Identifiers
EC no.	6.2.1.37
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

3-Hydroxybenzoate—CoA ligase (EC 6.2.1.37, 3-hydroxybenzoyl-CoA synthetase, 3-hydroxybenzoate-coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase) is an enzyme with systematic name 3-hydroxybenzoate:CoA ligase (AMP-forming).^[1] This enzyme catalyses the following chemical reaction

ATP + 3-hydroxybenzoate + CoA ${\displaystyle \rightleftharpoons }$ AMP + diphosphate + 3-hydroxybenzoyl-CoA

The enzyme works equally well with 4-hydroxybenzoate.

References

1. Laempe D, Jahn M, Breese K, Schägger H, Fuchs G (February 2001). "Anaerobic metabolism of 3-hydroxybenzoate by the denitrifying bacterium Thauera aromatica". Journal of Bacteriology. 183 (3): 968–79. doi:10.1128/jb.183.3.968-979.2001. PMC 94965. PMID 11208796.

External links

• 3-hydroxybenzoate—CoA+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)