The 2016 Belarusian Premier League was the 26th season of top-tier football in Belarus. The season began on 1 April 2016 and concluded on 27 November 2016. BATE Borisov were the defending champions, having won their 12th league title last year; they successfully defended their title this season.
Isloch spent the season at City Stadium in Molodechno, as their previous home venue RCOP-BGU Stadium in Minsk did not meet Premier League criteria. In addition, one game was played at KFP Minsk and one game at FC Minsk Stadium.