Ro20-8552

Ro20-8552

Legal status
Legal status	CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act
Identifiers
IUPAC name 8-chloro-5-(2-fluorophenyl)-7-methyl-1,3-dihydro-1,4-benzodiazepin-2-one
PubChem CID	44366138
ChemSpider	23222080
ChEMBL	ChEMBL356411
CompTox Dashboard (EPA)	DTXSID101337051
Chemical and physical data
Formula	C16H12ClFN2O
Molar mass	302.73 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=CC2=C(C=C1Cl)NC(=O)CN=C2C3=CC=CC=C3F
InChI InChI=1S/C16H12ClFN2O/c1-9-6-11-14(7-12(9)17)20-15(21)8-19-16(11)10-4-2-3-5-13(10)18/h2-7H,8H2,1H3,(H,20,21) Key:GANKBGRUGXCJBG-UHFFFAOYSA-N

Ro20-8552 is a benzodiazepine derivative with sedative and anxiolytic effects, which has been sold as a designer drug.^[1][2]

See also

• Ro05-2904
• Ro05-4435
• Ro05-4082
• Ro07-4065
• Ro20-8065

References

1. Zhang W, Koehler KF, Harris B, Skolnick P, Cook JM (March 1994). "Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors". Journal of Medicinal Chemistry. 37 (6): 745–57. doi:10.1021/jm00032a007. PMID 8145224.
2. Catalani V, Botha M, Corkery JM, Guirguis A, Vento A, Scherbaum N, Schifano F (July 2021). "The Psychonauts' Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity". Pharmaceuticals. 14 (8): 720. doi:10.3390/ph14080720. hdl:2299/24928. PMC 8398354. PMID 34451817.