Methoxyqualone

Methoxyqualone

Clinical data
ATC code	none
Identifiers
IUPAC name 3-(2-methoxyphenyl)-2-methylquinazolin-4(3H)-one
CAS Number	4260-28-0
PubChem CID	365324
ChemSpider	324297
ChEMBL	ChEMBL1990581
Chemical and physical data
Formula	C16H14N2O2
Molar mass	266.300 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=NC2=CC=CC=C2C(=O)N1C3=CC=CC=C3OC
InChI InChI=1S/C16H14N2O2/c1-11-17-13-8-4-3-7-12(13)16(19)18(11)14-9-5-6-10-15(14)20-2/h3-10H,1-2H3 Key:YIEVFKLHPPPUSM-UHFFFAOYSA-N

Methoxyqualone (2-Methoxyqualone) is a quinazolinone-class chemical compound which has been sold as a designer drug, first identified in Mongolia in 2022. It is closely related in structure to compounds such as etaqualone and nitromethaqualone which have previously been sold as designer drugs, and is presumed to have similar sedative effects.^[1][2][3][4]

See also

• Methaqualone
• Methylmethaqualone
• Mebroqualone
• Mecloqualone
• Cloroqualone

References

1. Yang H, Wang S, Qi H, Liu J, Wang Y, Gu J, et al. (July 2022). "2-Methoxyqualone, a new recreational drug, discovered from a package seized by the police: a preliminary report". Forensic Toxicology. 40 (2): 414–416. doi:10.1007/s11419-022-00626-w. PMID 36454416. S2CID 248347482.
2. Yang H, Wang Y, Liu J, Qiu S, Gu J, Bai H, et al. (January 2023). "The next addiction-causing drug class 4-quinazolinone derivatives: analyses of methaqualone analogs including recently discovered 2-methoxyqualone by different modes of mass spectrometry". Forensic Toxicology. 41 (1): 59–70. doi:10.1007/s11419-022-00631-z. PMID 36652055. S2CID 250077820.
3. Qiu S, Kang Y, Wang Y, Liu J, Yang H, Gu J, et al. (April 2023). "Quantification of a new recreational drug 2-methoxyqualone in human hair using gas chromatography-tandem mass spectrometry". Forensic Science International. 345: 111620. doi:10.1016/j.forsciint.2023.111620. PMID 36889066. S2CID 257244093.
4. Kuropka P, Zawadzki M, Szpot P (July 2023). "Emerging trends in methaqualone and analogues abuse: insights from online forums". Forensic Toxicology. 41 (2): 329–331. doi:10.1007/s11419-023-00665-x. PMID 37169943. S2CID 258638250.