Interleukin-1 receptor

See also: Interleukin-1 receptor family
interleukin 1 receptor, type I
Identifiers
SymbolIL1R1
Alt. symbolsIL1R, IL1RA
NCBI gene3554
HGNC5993
OMIM147810
RefSeqNM_000877
UniProtP14778
Other data
LocusChr. 2 q12
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 1 receptor, type II
Identifiers
SymbolIL1R2
Alt. symbolsIL1RB
NCBI gene7850
HGNC5994
OMIM147811
RefSeqNM_173343
UniProtP27930
Other data
LocusChr. 2 q12
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 1 receptor accessory protein
Identifiers
SymbolIL1RAP
Alt. symbolsIL-1RAcP, IL1R3, C3orf13
NCBI gene3556
HGNC5995
OMIM602626
RefSeqNM_134470
UniProtQ9NPH3
Other data
LocusChr. 3 q28
Search for
StructuresSwiss-model
DomainsInterPro

Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1.[1] Two forms of the receptor exist. The type I receptor is primarily responsible for transmitting the inflammatory effects of interleukin-1 (IL-1) while type II receptors may act as a suppressor of IL-1 activity by competing for IL-1 binding.[1] Also opposing the effects of IL-1 is the IL-1 receptor antagonist (IL-1RA).[2]

The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction.[3]

References

  1. ^ a b Kuno K, Matsushima K (1994). "The IL-1 receptor signaling pathway". J. Leukoc. Biol. 56 (5): 542–7. doi:10.1002/jlb.56.5.542. PMID 7964161. S2CID 43095473. Archived from the original (abstract page) on 2005-05-07. Retrieved 2008-02-28.
  2. ^ Arend WP (1991). "Interleukin 1 receptor antagonist. A new member of the interleukin 1 family". J. Clin. Invest. 88 (5): 1445–51. doi:10.1172/JCI115453. PMC 295645. PMID 1834696.
  3. ^ Wesche H, Korherr C, Kracht M, Falk W, Resch K, Martin MU (March 1997). "The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)". J. Biol. Chem. 272 (12): 7727–31. doi:10.1074/jbc.272.12.7727. PMID 9065432.


Stub icon

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

Read other articles:

دوري آيسلندا الممتاز 2009

يفتقر محتوى هذه المقالة إلى الاستشهاد بمصادر. فضلاً، ساهم في تطوير هذه المقالة من خلال إضافة مصادر موثوق بها. أي معلومات غير موثقة يمكن التشكيك بها وإزالتها. (نوفمبر 2019) دوري آيسلندا الممتاز 2009 تفاصيل الموسم دوري آيسلندا الممتاز  النسخة 98  البلد آيسلندا  التاريخ بدا...

 

الإسلام في جنوب السودان

جزء من سلسلة مقالات حولالإسلام حسب البلد الإسلام في إفريقيا أنغولا بنين بوتسوانا بوركينا فاسو بوروندي الكاميرون الرأس الأخضر أفريقيا الوسطى نشاد الجزائر جزر القمر الكونغو الديمقراطية الكونغو ساحل العاج جيبوتي مصر غينيا الاستوائية إريتريا إثيوبيا الغابون غامبيا غانا غين

 

Karbon dioksida

Karbon dioksida Nama Nama IUPAC Karbon dioksida Nama lain Gas asam karbonat; karbonat anhidrida; es kering (bentuk padat); zat asam arang Penanda Nomor CAS 124-38-9 Model 3D (JSmol) Gambar interaktif 3DMet {{{3DMet}}} Nomor EC PubChem CID 280 Nomor RTECS {{{value}}} CompTox Dashboard (EPA) DTXSID4027028 InChI InChI=1/CO2/c2-1-3 SMILES C(=O)=O Sifat Rumus kimia CO2 Massa molar 44,0095(14) g/mol Penampilan gas tidak berwarna Densitas 1.600 g/L (padat)1,98 g/L (gas) Titik lebur

Precesión de los equinoccios

Este artículo trata sobre la precesión del eje de rotación o el cambio en la inclinación orbital. Para la rotación de la órbita de un cuerpo celeste, véase Precesión apsidal. Movimientos de la Tierra: rotación, precesión y nutación. La proyección de la ruta de precesión del Polo Norte en el cielo fijo de la época J2000.0 para el intervalo de tiempo de 48000 a. C. a 52000 d. C.[1]​ En astronomía, la precesión de los equinoccios o precesión axial es el cambio le...

 

The Thirteenth Chair

The Thirteenth Chair kan verwijzen naar: The Thirteenth Chair (1919), een film van Léonce Perret The Thirteenth Chair (1929), een film van Tod Browning The Thirteenth Chair (1937), een film van George B. Seitz Bekijk alle artikelen waarvan de titel begint met The Thirteenth Chair of met The Thirteenth Chair in de titel. Dit is een doorverwijspagina, bedoeld om de verschillen in betekenis of gebruik van The Thirteenth Chair inzichtelijk te maken. Op deze pagina staat ...

 

Jane Froman

Jane FromanInformasi latar belakangNama lahirEllen Jane FromanLahir(1907-11-10)10 November 1907University City, MissouriMeninggal22 April 1980(1980-04-22) (umur 72)Columbia, MissouriPekerjaanPenyanyi, pemeranSitus webwww.janefroman.com Ellen Jane Froman (10 November 1907 – 22 April 1980) adalah seorang penyanyi dan pemeran Amerika Serikat. Pada masa karirnya selama tiga puluh tahun , Froman pentas di panggung, radio dan televisi meskipun mengalami masalah kesehatan kronis...

Louis I of Hungary

King of Hungary and Croatia from 1342 to 1382 Louis the Great redirects here. For the French king, see Louis XIV. Louis I the GreatLouis I as depicted in the Chronicon PictumKing of Hungary and CroatiaReign1342–1382CoronationSzékesfehérvár21 July 1342PredecessorCharles ISuccessorMary IKing of PolandReign1370–1382Coronation17 November 1370PredecessorCasimir IIISuccessorJadwigaBorn5 March 1326Visegrád, Kingdom of HungaryDied10 September 1382(1382-09-10) (aged 56)Nagyszombat, Kingdo...

 

Sint-Nicolaaskerk (Heythuysen)

Sint-Nicolaaskerk De Sint-Nicolaaskerk is de parochiekerk van Heythuysen, gelegen aan Dorpstraat 120, gesitueerd in de Midden-Limburgse gemeente Leudal. Naast de kerk staat de Missiekapel. Geschiedenis Niet lang na 1504 werd deze laatgotische bakstenen pseudobasiliek gebouwd. In 1847 werd de oorspronkelijke toren door de huidige, neogotische, toren vervangen en werd het schip vergroot met twee traveeën. In 1927 werden de huidige zijbeuken gebouwd. Deze zijn niet alleen breed, maar ook even h...

 

Луценко, Роман Васильевич

В Википедии есть статьи о других людях с такой фамилией, см. Луценко. Роман Луценко Общая информация Полное имя Роман Васильевич Луценко Родился 20 января 1985(1985-01-20)[1] (38 лет)Глухов, Сумская область, Украинская ССР, СССР Гражданство  Украина Рост 178 см Позиция полузащи...

Ballaugh

Human settlement in the United KingdomBallaughManx: Balley ny LougheyMain road at Ballaugh BridgeBallaughLocation within the Isle of ManPopulation1,032 (2016 Census)OS grid referenceSC345936ParishBallaughSheadingMichaelCrown dependencyIsle of ManPost townISLE OF MANPostcode districtIM7Dialling code01624PoliceIsle of ManFireIsle of ManAmbulanceIsle of Man House of KeysAyre & Michael List of places Isle of Man 54°18′40″N 4°32′38″W࿯...

 

One Night Stand (American TV series)

Some of this article's listed sources may not be reliable. Please help this article by looking for better, more reliable sources. Unreliable citations may be challenged or deleted. (June 2022) (Learn how and when to remove this template message) American TV series or program One Night StandGenreStand-up comedyCountry of originUSAOriginal languageEnglishNo. of seasons5No. of episodes65ProductionRunning time30 minutesOriginal releaseNetworkHBO One Night Stand is an HBO stand-up series that...

 

Фріденталь Михайло Борисович

Михайло Фріденталь Відкриття пам'ятника Івану Котляревському, Полтава, 1903. Автор М. Б. ФрідентальІм'я при народженні Меєр-Хацк чи МойсейНародився 1868(1868)ПолтаваПомер 1935(1935)ХарківПідданство Російська імперія  УНР  СРСРНаціональність єврейМісце проживання ПолтаваДія...

Heather Mitts

American soccer player Heather Mitts Mitts in May 2010Personal informationFull name Heather Mitts FeeleyBirth name Heather Blaine Mitts[1]Date of birth (1978-06-09) June 9, 1978 (age 45)Place of birth Cincinnati, OhioHeight 5 ft 5 in (1.65 m)Position(s) Defender / Right backCollege careerYears Team Apps (Gls)1996–1999 Florida Gators Senior career*Years Team Apps (Gls)2000 Tampa Bay Extreme 2001–2003 Philadelphia Charge 51 (0)2005 Central Florida Krush 4 (0)2009...

 

Necochea

City in Buenos Aires, ArgentinaNecocheaCityNecocheaLocation in ArgentinaCoordinates: 38°32′S 58°45′W / 38.533°S 58.750°W / -38.533; -58.750Country ArgentinaProvince Buenos AiresPartidoNecocheaFoundedOctober 12, 1881; 142 years ago (1881-10-12)Government • IntendantArturo Rojas (Nueva Necochea)Elevation16 m (52 ft)Population (2010 census [INDEC]) • Total90,000CPA BaseB 7630Area code+54 2262ClimateCfbW...

 

Вошива (притока Берестової)

У Вікіпедії є статті про інші значення цього терміна: Вошива. Вошива 49°12′51″ пн. ш. 35°15′57″ сх. д. / 49.21440000002777282° пн. ш. 35.2658800000277779° сх. д. / 49.21440000002777282; 35.2658800000277779Витік на східному боці від села АнтонівкиГирло БерестоваПохил, м/км 0,94 м/кмБасей...

Burning in the Skies

Burning in the Skiessingolo discograficoScreenshot tratto dal video del branoArtistaLinkin Park Pubblicazione21 marzo 2011(vedi date di pubblicazione) Durata4:13 (versione album)4:00 (versione radiofonica) Album di provenienzaA Thousand Suns GenereRock alternativo[1] EtichettaWarner Bros., Machine Shop ProduttoreMike Shinoda, Rick Rubin Registrazione2008–2010, NRG Recording Studios, North Hollywood (California) FormatiCD, download digitale, streaming Linkin Park - cronologiaSingolo ...

 

Robert R. Redfield

Halaman ini berisi artikel tentang virologis dan peneliti medis Amerika Serikat. Untuk antropolog Amerika Serikat, lihat Robert Redfield. Robert R. RedfieldDirektur Pusat Pengendalian dan Pencegahan Penyakit ke-18Masa jabatan26 Maret 2018 – 20 Januari 2021PresidenDonald TrumpWakilAnne SchuchatPendahuluBrenda FitzgeraldPenggantiRochelle Walensky Informasi pribadiLahirRobert Ray Redfield Jr.10 Juli 1951 (umur 72)Bethesda, MarylandPendidikanUniversitas Georgetown (BS, 1973; MD, 1...

 

Cansei de Ser Sexy

For the band, see CSS (band). 2005 studio album by CSSCansei de Ser SexyStudio album by CSSReleasedOctober 9, 2005 (2005-10-09)RecordedMarch–June 2005StudioJägermeister Bitte (a.k.a. Adriano's and Carolina's home), São Paulo, BrazilGenrePunk funk[1]Length 47:50 (original version) 34:38 (international version) LabelTramaProducerAdriano CintraCSS chronology A Onda Mortal / Uma Tarde com PJ(2004) Cansei de Ser Sexy(2005) Donkey(2008) Alternative coverInternatio...

Châtenay-Malabry

You can help expand this article with text translated from the corresponding article in French. (July 2014) Click [show] for important translation instructions. View a machine-translated version of the French article. Machine translation, like DeepL or Google Translate, is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-translated text into the English Wikipedia...

 

A Somewhat Gentle Man

2010 film You can help expand this article with text translated from the corresponding article in Norwegian. (May 2012) Click [show] for important translation instructions. View a machine-translated version of the Norwegian article. Machine translation, like DeepL or Google Translate, is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-translated text into the En...

 

Strategi Solo vs Squad di Free Fire: Cara Menang Mudah!