Congenital disorder of a limb
Dysmelia (from the Greek dys (δυσ-), "bad" + mélos (μέλος), "limb" + English suffix -ia) is a congenital disorder of a limb resulting from a disturbance in embryonic development.[1]
Types
Dysmelia can refer to [citation needed]
- missing (aplasia) limbs: amelia, oligodactyly, congenital amputation e.g. tibial or radial aplasia
- malformation of limbs: shortening (micromelia, rhizomelia or mesomelia), ectrodactyly, phocomelia, meromelia, syndactyly, brachydactyly, club foot
- extra limbs: polymelia, polydactyly, polysyndactyly
- others: tetraamelia, hemimelia, symbrachydactyly
Occurrence rate
Birth defects involving limbs occur in 0.69 per 1000.[2]
Causes
Dysmelia can be caused by[citation needed]
Syndromes with dysmelia
References
- ^ "Dysmelia (Limb Deficiency/Reduction)". Atlas of Genetic Diagnosis and Counseling. Humana Press. 2006. pp. 312–322.
- ^ McGuirk, Caroline K.; Westgate, Marie-Noel; Holmes, Lewis B. (2001-10-01). "Limb Deficiencies in Newborn Infants". Pediatrics. 108 (4). American Academy of Pediatrics (AAP): e64. doi:10.1542/peds.108.4.e64. ISSN 1098-4275. PMID 11581472. S2CID 1863175.
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