Medical condition
Meromelia is a birth defect characterized by the lacking of a part, but not all, of one or more limbs with the presence of a hand or foot. It results in a shrunken and deformed extremity.[ 1]
Cause
Such defects are mainly the results of genetic disorders , but some teratogenic (or environmental) factors have been identified, such as the use of thalidomide from 1957 to 1962 for morning sickness (NVP).[ 1]
Diagnosis
Meromelia is a birth defect characterized by lacking part of at least one free limb.[ 2]
Epidemiology
Approximately 0.00001.4% of live births result in meromelia.[ 3]
Etymology
The word meromelia comes from the Greek meros melia [ 4]
See also
References
^ a b Sadler, T. W. Langman's Medical Embryology Eleventh Ed.. LWW, p. 140.
^ Davis, Donald D.; Kane, Steven M. (2023), "Meromelia" , StatPearls , Treasure Island (FL): StatPearls Publishing, PMID 32809600 , retrieved 2023-09-30 ^ Özdemir, Meltem; Kavak, Rasime Pelin; Eraslan, Önder (June 24, 2019). "Upper Limb Meromelia with Oligodactyly and Brachymesophalangy of the Foot: An Unusual Association" . Case Reports in Radiology . 2019 . Hindawi Limited: 1–5. doi :10.1155/2019/3419383 ISSN 2090-6862 . PMC 6612976 PMID 31341693 . ^ "Nomenclature for Congenital Skeletal Limb Deficiencies, a Revision of the Frantz and O'Rahilly Classification" (PDF) . Artificial Limbs: A Review of Current Developments . 2 (1). 1966 – via Orthotics & Prosthetics Library.
