16-hydroxysteroid epimerase

16-hydroxysteroid epimerase
Identifiers
EC no.5.1.99.2
CAS no.37318-40-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 16-hydroxysteroid epimerase (EC 5.1.99.2) is an enzyme that catalyzes the chemical reaction

16alpha-hydroxysteroid 16beta-hydroxysteroid

Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.

References

  • Dahm K, Lindlau M, Breuer H (1968). "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta. 159 (2): 377–89. doi:10.1016/0005-2744(68)90086-7. PMID 5657462.


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