^Bugenhagen: Lifestream... In other words, a path of energy of the souls roaming the Planet. 'Spirit Energy' is a word that you should never forget.(Final Fantasy VII)
^Cloud: If the Spirit energy is lost, our Planet is destroyed...(Final Fantasy VII)
^Bugenhagen: Ho Ho Hoooo. Spirit energy is efficient BECAUSE it exists within nature. When Spirit energy is forcefully extracted, and manufactured, it can't accomplish its true purpose. / Cloud: You're talking about Mako energy, right? / Bugenhagen: Every day Mako reactors suck up Spirit energy, diminishing it. Spirit energy gets compressed in the reactors and processed into Mako energy. All living things are being used up and thrown away. In other words, Mako energy will only destroy the Planet...(Final Fantasy VII)
^Marlene: The Shinra Electric Power Company discovered a way to use the Lifestream as an energy source.(Advent Children)
^Sephiroth: Normal members of SOLDIER are humans that have been showered with Mako. You're different from the others, but still human.(Final Fantasy VII)
^Sephiroth: Our mission is to investigate an old Mako reactor. There have been reports of it malfunctioning, and producing brutal creatures. First, we will dispose of those creatures. Then, we'll locate the problem and neutralize it. / Cloud: Brutal creatures... Where? / Sephiroth: The Mako Reactor at Nibelheim.(Final Fantasy VII)
^Marlene: Anyway, there was one SOLDIER named Sephiroth, who was better than the rest.(Advent Children)
^Ifalna: That's when the one who injured the Planet... or the 'crisis from the sky', as we call him, came. He first approached as a friend, deceived them, and finally...... gave them the virus. The Cetra were attacked by the virus and went mad... transforming into monsters. Then, just as he had at the Knowlespole. He approached other Cetra clans...... infecting them with... the virus...(Final Fantasy VII)
^Sephiroth: ...an organism that was apparently dead, was found in a 2000 year old geological stratum. Professor Gast named that organism, Jenova...X Year, X Month, X Day. Jenova confirmed to be an Ancient...X Year, X Month, X Day. Jenova Project approved. The use of Mako Reactor 1 approved for use...(Final Fantasy VII)
^Sephiroth: You ignorant traitor. I'll tell you. This Planet originally belonged to the Cetra. Cetra was an itinerant race. They would migrate in, settle the Planet, then move on...At the end of their harsh, hard journey, they would find the Promised Land and supreme happiness. But, those that disliked the journey appeared. Those who stopped their migrations built shelters and elected to lead an easier life. They took that which the Cetra and the planet had made without giving back one whit in return! Those are your ancestors. / Cloud: Sephiroth... / Sephiroth: Long ago, disaster struck this planet. Your ancestors escaped... They survived because they hid. The Planet was saved by sacrificing the Cetra. After that, your ancestors continued to increase. Now all that's left of the Cetra is in these reports. / Cloud: What does that have to do with you? / Sephiroth: Don't you get it? An Ancient named Jenova was found in the geological stratum of 2000 years ago. The Jenova Project. The Jenova Project wanted to produce people with the powers of the Ancients...... no, the Cetra....I am the one that was produced.(Final Fantasy VII)
^Doctor: I'll say it again, he's got Mako poisoning. I've never seen a case this bad...An immense amount of Mako-drenched knowledge was put into his brain all at once......(Final Fantasy VII)