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新鮮冷凍血漿
	一袋恰好為一單位的新鮮冷凍血漿
臨床資料
其他名稱	放血後24小時內的冷凍血漿（FP24）
AHFS/Drugs.com	Micromedex详细消费者药物信息
ATC碼	B05AX03 (WHO) ;
识别信息
ChemSpider	無;

新鮮冷凍血漿（fresh frozen plasma, FFP）為一從全血製備而成的血液製品^[3]，一般是在採集全血後八小時內分離製備^[4]，用於治療體內凝血因子過低（INR>1.5）或是血漿蛋白過少之患者^[3]^[1]，也做為血漿置換的置換液^[2]^[5]，通常會建議（但非必要）使用ABO血型相符的血漿^[6]^[7]。不建議使用新鮮冷凍血漿作為代用血漿（英语：volume expander）^[3]。使用方式為緩慢輸注至靜脈內^[2]。

副作用包含噁心和發癢^[3]，並有低機率發生過敏反應、血栓，或感染^[3]^[1]。在懷孕期間或哺乳期間使用，對嬰兒的安全性仍未知^[2]。患有蛋白質S缺乏症（英语：protein S deficiency）、免疫球蛋白A缺乏（英语：IgA deficiency），或心臟衰竭的病人在使用上須特別注意^[2]。新鮮冷凍血漿是由水，蛋白質，碳水化合物，脂質，與維生素組成的複雜混合物^[1]。零下18度冷凍下可保存約一年^[1]。

第二次世界大戰期間血漿製品第一次被應用於醫療中^[1]^[8]，名列世界衛生組織基本藥物清單，該清單羅列一個健康照護體系中所需要的各項最安全有效的藥物。^[9]。在英國一單位的新鮮冷凍血漿價錢約30英磅^[10]。亦有其他種類的新鮮冷凍血，包含採血後24小時內冷凍血漿（英语：Plasma frozen within 24 hours）、冷凍沉澱品減除血漿（英语：Cryoprecipitate reduced plasma）、冷凍血漿、以及溶劑清潔劑處理血漿^[1]。其中冷凍血漿類似新鮮冷凍血漿，不過是在採集全血八小時分離，在零下18度冰箱可存放五年^[4]。

參考資料

^ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Shaz, Beth H.; Hillyer, Christopher D.; Roshal, Mikhail; Abrams, Charles S. Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects. Newnes. 2013: 209–212. ISBN 9780123977885. （原始内容存档于2017-09-23）.
^ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Plasma Intravenous Advanced Patient Information - Drugs.com. www.drugs.com. [10 January 2017]. （原始内容存档于11 January 2017）.
^ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 British national formulary : BNF 69 69. British Medical Association. 2015: 172. ISBN 9780857111562.
^ ^4.0 ^4.1 台灣血液學基金會血液成分精要 (PDF). [2019-03-25]. （原始内容存档 (PDF)于2018-03-04）.
^ Schwartz, Joseph; Padmanabhan, Anand; Aqui, Nicole; Balogun, Rasheed A.; Connelly-Smith, Laura; Delaney, Meghan; Dunbar, Nancy M.; Witt, Volker; Wu, Yanyun. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue. Journal of Clinical Apheresis. June 2016, 31 (3): 149–338. ISSN 0733-2459. doi:10.1002/jca.21470.
^ Sikka, Paul K.; Beaman, Shawn T.; Street, James A. Basic Clinical Anesthesia. Springer. 2015: 102 [2019-03-25]. ISBN 9781493917372. （原始内容存档于2019-05-19）（英语）.
^ Aglio, Linda S.; Lekowski, Robert W.; Urman, Richard D. Essential Clinical Anesthesia Review: Keywords, Questions and Answers for the Boards. Cambridge University Press. 2015: 218 [2019-03-25]. ISBN 9781107681309. （原始内容存档于2019-05-19）（英语）.
^ Plasma Equipment and Packaging, and Transfusion Equipment. [2019-03-25]. （原始内容存档于2017-06-09）.
^ WHO Model List of Essential Medicines (19th List) (PDF). World Health Organization. April 2015 [8 December 2016]. （原始内容存档 (PDF)于13 December 2016）.
^ Yentis, Steven M.; Hirsch, Nicholas P.; Ip, James. Anaesthesia and Intensive Care A-Z: An Encyclopedia of Principles and Practice. Elsevier Health Sciences. 2013: 147. ISBN 9780702053757. （原始内容存档于2017-09-23）.

延伸閱讀

British Committee for Standards in Haematology, Blood Transfusion Task Force (J. Duguid, Chairman); O'Shaughnessy, D. F.; Atterbury, C.; Bolton Maggs, P.; Murphy, M.; Thomas, D.; Yates, S.; Williamson, L. M. Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. British Journal of Haematology. 1 July 2004, 126 (1): 11–28. ISSN 1365-2141. PMID 15198728. doi:10.1111/j.1365-2141.2004.04972.x.

外部連結

[Sh2013-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Shaz, Beth H.; Hillyer, Christopher D.; Roshal, Mikhail; Abrams, Charles S. Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects. Newnes. 2013: 209–212. ISBN 9780123977885. （原始内容存档于2017-09-23）.

[Drugs2017-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Plasma Intravenous Advanced Patient Information - Drugs.com. www.drugs.com. [10 January 2017]. （原始内容存档于11 January 2017）.

[BNF69-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 British national formulary : BNF 69 69. British Medical Association. 2015: 172. ISBN 9780857111562.

[血液成分精要-4] 4.0 ^4.1 台灣血液學基金會血液成分精要 (PDF). [2019-03-25]. （原始内容存档 (PDF)于2018-03-04）.

[5] Schwartz, Joseph; Padmanabhan, Anand; Aqui, Nicole; Balogun, Rasheed A.; Connelly-Smith, Laura; Delaney, Meghan; Dunbar, Nancy M.; Witt, Volker; Wu, Yanyun. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue. Journal of Clinical Apheresis. June 2016, 31 (3): 149–338. ISSN 0733-2459. doi:10.1002/jca.21470.

[6] Sikka, Paul K.; Beaman, Shawn T.; Street, James A. Basic Clinical Anesthesia. Springer. 2015: 102 [2019-03-25]. ISBN 9781493917372. （原始内容存档于2019-05-19）（英语）.

[7] Aglio, Linda S.; Lekowski, Robert W.; Urman, Richard D. Essential Clinical Anesthesia Review: Keywords, Questions and Answers for the Boards. Cambridge University Press. 2015: 218 [2019-03-25]. ISBN 9781107681309. （原始内容存档于2019-05-19）（英语）.

[8] Plasma Equipment and Packaging, and Transfusion Equipment. [2019-03-25]. （原始内容存档于2017-06-09）.

[WHO19th-9] WHO Model List of Essential Medicines (19th List) (PDF). World Health Organization. April 2015 [8 December 2016]. （原始内容存档 (PDF)于13 December 2016）.

[Yen2013-10] Yentis, Steven M.; Hirsch, Nicholas P.; Ip, James. Anaesthesia and Intensive Care A-Z: An Encyclopedia of Principles and Practice. Elsevier Health Sciences. 2013: 147. ISBN 9780702053757. （原始内容存档于2017-09-23）.

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