SERPINB9
เซอร์ปิน บี9 (อังกฤษ : Serpin B9 หรือ SERPINB9) เป็นโปรตีน ในมนุษย์ที่ถูกถอดรหัสโดยยีน SERPINB9 บนโครโมโซมคู่ที่ 6 [ 5] [ 6] [ 7] มหาวงศ์ เซอร์ปิน (serine proteinase inhibitors;serpins) ที่ทำหน้าที่เข้าจับและยับยั้งการทำงานของเอนไซม์ซีรีนโปรตีเอส (serine proteinase) ซึ่งส่งผลต่อกระบวนการต่างๆภายในเซลล์หลายอย่าง อาทิ การจับลิ่มของเลือด , ปฏิกิริยาการตรึงคอมพลีเมนต์ , การสร้างเมทริกซ์ , การเกิดอะพอพโทซิส ของเซลล์[ 7]
↑ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000170542 – Ensembl , May 2017↑ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000045827 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors" . J Biol Chem . 270 (50): 29854–61. doi :10.1074/jbc.270.50.29854 PMID 8530382 . ↑ Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI (Feb 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet . 82 (3–4): 273–7. doi :10.1159/000015118 . PMID 9858835 . ↑ 7.0 7.1 "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9" .
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