PROFILBARU.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

S-metil-5'-tioadenozin fosforilaza
S-metil-5'-tioadenozin fosforilaza
Identifikatori
EC broj	2.4.2.28
CAS broj	61970-06-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

S-metil-5'-tioadenozin fosforilaza (EC 2.4.2.28, 5'-metiltioadenozin nukleozidaza, 5'-dezoksi-5'-metiltioadenozin fosforilaza, MTA fosforilaza, MeSAdo fosforilaza, MeSAdo/Ado fosforilaza, metiltioadenozin fosforilaza, metiltioadenozin nukleozid fosforilaza, 5'-metiltioadenozin:fosfat metiltio-D-ribozil-transferaza, S-metil-5-tioadenozin fosforilaza, S-metil-5-tioadenozin:fosfat S-metil-5-tio-alfa-D-ribozil-transferaza) je enzim sa sistematskim imenom S-metil-5'-tioadenozin:fosfat S-metil-5-tio-alfa-D-ribozil-transferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-metil-5'-tioadenozin + fosfat

\rightleftharpoons

adenin + S-metil-5-tio-alfa-D-riboza 1-fosfat

Ovaj enzim takođe deluje na 5'-dezoksiadenozin i druge analoge sa 5'-dezoksi grupama.

Reference

^ Carteni-Farina, M., Oliva, A., Romeo, G., Napolitano, G., De Rosa, M., Gambacorta, A. and Zappia, V. (1979). „5′-Methylthioadenosine phosphorylase from Caldariella acidophila. Purification and properties”. Eur. J. Biochem. 101: 317—324. PMID 118001.
^ Garbers, D.L. (1978). „Demonstration of 5′-methylthioadenosine phosphorylase activity in various rat tissues. Some properties of the enzyme from rat lung”. Biochim. Biophys. Acta. 523: 82—93. PMID 415762.
^ Pegg, A.E. & Williams-Ashman, H.G. (1969). „Phosphate-stimulated breakdown of 5′-methylthioadenosine by rat ventral prostate”. Biochem. J. 115: 241—247. PMID 5378381.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

S-methyl-5'-thioadenosine+phosphorylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Carteni-Farina, M., Oliva, A., Romeo, G., Napolitano, G., De Rosa, M., Gambacorta, A. and Zappia, V. (1979). „5′-Methylthioadenosine phosphorylase from Caldariella acidophila. Purification and properties”. Eur. J. Biochem. 101: 317—324. PMID 118001.

[2] Garbers, D.L. (1978). „Demonstration of 5′-methylthioadenosine phosphorylase activity in various rat tissues. Some properties of the enzyme from rat lung”. Biochim. Biophys. Acta. 523: 82—93. PMID 415762.

[3] Pegg, A.E. & Williams-Ashman, H.G. (1969). „Phosphate-stimulated breakdown of 5′-methylthioadenosine by rat ventral prostate”. Biochem. J. 115: 241—247. PMID 5378381.

[1]

[2]

[3]