Nepentezin

Nepentezin
Identifikatori
EC broj	3.4.23.12
CAS broj	9073-80-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Nepentezin (EC 3.4.23.12, nepentesna aspartička proteinaza, nepentesno kiselinska proteinaza, nepentacin, nepentazin, aspartilna endopeptidaza) je enzim.^{[1][2][3][4][5][6]} Ovaj enzim katalizuje sledeću hemijsku reakciju

Specifičnost je slična pepsinu, ali dodatno se razlažu veze na obe strane ostatka Asp i u Lys-Arg

Ovaj enzim je prisutan u biljkama Nepenthes spp. i Drosera peltata.

Reference

1. Amagase, S., Nakayama, S. and Tsugita, A. (1969). „Acid protease in Nepenthes. II. Study on the specificty of nepenthesin”. J. Biochem. (Tokyo). 66: 431—439. PMID 5354017. CS1 одржавање: Вишеструка имена: списак аутора (веза)
2. Garg, G.K. & Virupaksha, T.K. (1970). „Acid protease from germinated sorghum. 2. Substrate specificity with synthetic peptides and ribonuclease A”. Eur. J. Biochem. 17: 4—12. PMID 5486576. 
3. Shinano, S. & Fukushima, K. (1971). „Studies on lotus seed protease. Part III. Some physicochemical and enzymic properties”. Agric. Biol. Chem. 35: 1488—1494. 
4. Amagase, S. (1972). „Digestive enzymes in insectivorous plants. III. Acid proteases in the genus Nepenthes and Drosera peltata”. J. Biochem. (Tokyo). 72: 73—81. PMID 5069751. 
5. Takahashi, K., Chang, W-J. and Ko, J-S. (1974). „Specific inhibition of acid proteases from brain, kidney, skeletal muscle, and insectivorous plants by diazoacetyl-DL-norleucine methyl ester and by pepstatin”. J. Biochem. (Tokyo). 76: 897—899. PMID 4436292. CS1 одржавање: Вишеструка имена: списак аутора (веза)
6. Tökés, Z.A., Woon, W.C. and Chambers, S.M. (1974). „Digestive enzymes secreted by the carnivorous plant Nepenthes macferlani L”. Planta. 119: 39—46. PMID 16526095. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

• Nepenthesin на US National Library of Medicine Medical Subject Headings (MeSH)