Hondroitin 6-sulfotransferaza

Hondroitin 6-sulfotransferaza
Identifikatori
EC broj	2.8.2.17
CAS broj	37292-93-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Hondroitin 6-sulfotransferaza (EC 2.8.2.17, hondroitinska 6-O-sulfotransferaza, 3'-fosfoadenozin 5'-fosfosulfat (PAPS):hondroitin sulfat sulfotransferaza, terminalna 6-sulfotransferaza) je enzim sa sistematskim imenom 3'-fosfoadenilil-sulfat:hondroitin 6'-sulfotransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

3'-fosfoadenilil sulfat + hondroitin ${\displaystyle \rightleftharpoons }$ adenozin 3',5'-bisfosfat + hondroitin 6'-sulfat

Sulfacija se odvija u 6-poziciji N-acetilgalaktozaminskih ostataka hondroitina.

Reference

1. Habuchi, O. & Miyashita, N. (1982). „Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage”. Biochim. Biophys. Acta. 717: 414—421. PMID 6957247. 

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

• Chondroitin+6-sulfotransferase на US National Library of Medicine Medical Subject Headings (MeSH)