Globotriozilkeramid b-1,6-N-acetilgalaktozaminil-transferaza

Globotriozilkeramid b-1,6-N-acetilgalaktozaminil-transferaza
Identifikatori
EC broj	2.4.1.154
CAS broj	62213-46-1
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Globotriozilkeramid b-1,6-N-acetilgalaktozaminil-transferaza (EC 2.4.1.154, globozid N-acetilgalaktozaminiltransferaza, uridin difosfoacetilgalaktozamin-glikosfingolipid acetilgalaktozaminiltransferaza, glikosfingolipid beta-N-acetilgalaktozaminiltransferaza, GalNAc transferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-galaktozamin-globotriosilkeramid beta-1,6-N-acetilgalaktozaminiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-N-acetil-D-galaktozamin + globotriozilkeramid ${\displaystyle \rightleftharpoons }$ UDP + globotetraozilkeramid

Ovaj enzim je visoko specifičan za akceptor. On ne deluje na globotetraozilkeramid ili laktozilkeramid.

Reference

1. Lockney, M.W. & Sweeley, C.C. (1982). „Characterization of a glycosphingolipid β-N-acetylgalactosaminyl-transferase activity in cultured hamster (nil) cells”. Biochim. Biophys. Acta. 712: 234—241. PMID 6812637. 

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

• Globotriosylceramide+beta-1,6-N-acetylgalactosaminyl-transferase на US National Library of Medicine Medical Subject Headings (MeSH)